Table 1 Baseline characteristics of diabetes and prediabetes subjects
Characteristic | Tertiles of NLR levels | Â | Â | Tertiles of NLR levels | Â | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Diabetes | Prediabetes | ||||||||||
Total (n = 7246) | Tertile 1 (n = 2415) | Tertile 2 (n = 2406) | Tertile 3 (n = 2425) | P value |  | Total (n = 13,024) | Tertile 1 (n = 3911) | Tertile 2 (n = 3868) | Tertile 3 (n = 3887) | P value | |
NLR | 2.34(0.02) | 1.33(0.01) | 2.08(0.01) | 3.41(0.02) | < 0.0001 |  | 2.13(0.01) | 1.26(0.01) | 1.93(0.00) | 3.11(0.01) | < 0.0001 |
Age, years | 58.6( 0.26) | 56.8(0.42) | 58.1(0.42) | 60.5(0.38) | < 0.0001 |  | 52.0(0.23) | 50.6(0.35) | 51.0(0.29) | 54.3(0.31) | < 0.0001 |
Male | 3732(51.50) | 1113(44.64) | 1223(50.88) | 1396(56.72) | < 0.0001 |  | 6853(52.62) | 2204(49.94) | 2228(52.40) | 2421(54.11) | 0.02 |
Race/ethnicity |  |  |  |  | < 0.0001 |  |  |  |  |  | < 0.0001 |
 Hispanic Mexican | 1604(22.14) | 516(11.45) | 580(10.61) | 508( 8.52) |  |  | 2355(18.08) | 758(9.78) | 873(9.84) | 724(7.66) |  |
 Non-Hispanic black | 1699(23.45) | 819(22.91) | 501(12.18) | 379( 8.06) |  |  | 2744(21.07) | 1412(19.18) | 757( 9.34) | 575( 6.72) |  |
 Non-Hispanic white | 2579(35.59) | 585(47.63) | 851(61.73) | 1143(72.03) |  |  | 5437(41.75) | 1283(54.93) | 1802(67.28) | 2352(74.70) |  |
 Others | 1364(18.82) | 495(18.00) | 474(15.48) | 395(11.39) |  |  | 2488(19.1) | 944(16.10) | 847(13.54) | 697(10.92) |  |
Education level |  |  |  |  | < 0.001 |  |  |  |  |  | 0.24 |
 Less than high school | 2768(38.2) | 975(29.96) | 921(24.90) | 873(23.29) |  |  | 3830(29.41) | 1294(20.93) | 1264(19.02) | 1272(20.11) |  |
 High school or equivalent | 1654(22.83) | 554(25.43) | 504(23.43) | 594(27.79) |  |  | 3051(23.43) | 999(23.45) | 1030(24.94) | 1022(25.68) |  |
 College or above | 2824(38.97) | 886(44.61) | 981(51.67) | 958(48.93) |  |  | 6143(47.17) | 2104(55.62) | 1985(56.04) | 2054(54.21) |  |
Martial | Â | Â | Â | Â | 0.71 | Â | Â | Â | Â | Â | 0.01 |
 Married/Cohabitating | 4409(60.85) | 1467(63.96) | 1473(63.04) | 1469(64.50) |  |  | 8189(62.88) | 2769(69.54) | 2699(66.83) | 2769(69.54) |  |
 Not married | 2837(39.15) | 948(36.04) | 933(36.96) | 956(35.50) |  |  | 4835(37.12) | 1510(30.46) | 1649(33.17) | 1510(30.46) |  |
Family income-poverty ratio |  |  |  |  | < 0.001 |  |  |  |  |  | 0.03 |
 <1 | 1675(23.12) | 592(18.97) | 544(15.47) | 539(15.07) |  |  | 2613(20.06) | 916(14.95) | 844(12.79) | 853(13.36) |  |
 1–3 | 3399(46.91) | 1136(44.18) | 1100(39.73) | 1163(41.57) |  |  | 5675(43.57) | 1880(37.87) | 1859(36.92) | 1936(39.60) |  |
 >=3 | 2172(29.98) | 687(36.85) | 762(44.79) | 723(43.36) |  |  | 4736(36.36) | 1601(47.18) | 1576(50.29) | 1559(47.04) |  |
Drinking status | Â | Â | Â | Â | 0.01 | Â | Â | Â | Â | Â | 0.01 |
 Non-drinker | 1327(18.31) | 486(18.40) | 451(16.96) | 390(13.60) |  |  | 1893(14.53) | 684(13.04) | 612(10.41) | 597(10.96) |  |
 Ever drinker | 5919(81.69) | 1929(81.60) | 1955(83.04) | 2035(86.40) |  |  | 11,131(85.47) | 3713(86.96) | 3667(89.59) | 3751(89.04) |  |
Smoking status |  |  |  |  | 0.004 |  |  |  |  |  | < 0.0001 |
 Never | 3688(50.9) | 1328(54.18) | 1246(51.27) | 1114(46.56) |  |  | 6848(52.58) | 2510(56.37) | 2247(51.12) | 2091(47.26) |  |
 Ever | 2392(33.01) | 715(30.12) | 783(31.80) | 894(36.41) |  |  | 3484(26.75) | 1067(25.40) | 1153(28.41) | 1264(28.99) |  |
 Current | 1166(16.09) | 372(15.70) | 377(16.93) | 417(17.04) |  |  | 2692(20.67) | 820(18.23) | 879(20.47) | 993(23.75) |  |
BMI, kg/m² | 32.66( 0.14) | 31.89(0.19) | 33.04(0.22) | 32.93(0.25) | < 0.0001 |  | 30.02(0.09) | 29.56(0.13) | 30.12(0.15) | 30.33(0.16) | < 0.001 |
HbA1c,% | 7.17(0.03) | 7.26(0.05) | 7.20(0.05) | 7.08(0.05) | 0.05 |  | 5.64(0.01) | 5.66(0.01) | 5.63(0.01) | 5.62(0.01) | < 0.0001 |
History of CVD | 1713(23.64) | 449(16.90) | 540(21.42) | 724(26.71) | < 0.001 |  | 1442(11.07) | 370( 7.92) | 413( 8.40) | 659(12.77) | < 0.0001 |
History of hypertension | 5147(71.03) | 1670(65.48) | 1666(66.45) | 1811(72.20) | < 0.001 |  | 6242(47.93) | 1982(41.93) | 1955(42.79) | 2305(49.95) | < 0.0001 |
Hyperlipidemia | 6260(86.39) | 2075(86.90) | 2082(88.40) | 2103(87.73) | 0.5 | Â | 10,203(78.34) | 3400(78.13) | 3358(79.45) | 3445(79.87) | 0.31 |
History of cancer | 937(12.93) | 237(11.84) | 312(14.61) | 388(16.84) | 0.003 |  | 1305(10.02) | 340( 8.89) | 378(10.10) | 587(13.59) | < 0.0001 |
History of COPD | 392(5.41) | 86(3.43) | 129(5.59) | 177(7.04) | 0.001 | Â | 551(4.23) | 137(3.77) | 170(4.49) | 244(5.29) | 0.03 |
Depression status | 1970(27.19) | 637(24.44) | 633(25.66) | 700(26.52) | 0.47 | Â | 2538(19.49) | 838(19.14) | 801(18.49) | 899(20.63) | 0.16 |
Anemia | 1081(14.92) | 302( 9.43) | 341(10.89) | 438(13.25) | 0.001 |  | 1054(8.09) | 406(7.16) | 285(4.54) | 363(6.19) | < 0.0001 |
HEI scores | 51.38(0.24) | 52.08(0.41) | 51.15(0.38) | 51.03(0.38) | 0.11 | Â | 50.32(0.21) | 50.93(0.30) | 50.15(0.31) | 49.94(0.32) | 0.04 |
Physical activity | Â | Â | Â | Â | 0.01 | Â | Â | Â | Â | Â | 0.41 |
 Low | 3093(42.69) | 1093(42.34) | 1017(41.38) | 983(36.93) |  |  | 4537(34.84) | 1521(34.62) | 1496(35.33) | 1520(33.65) |  |
 High | 4153(57.31) | 1322(57.66) | 1389(58.62) | 1442(63.07) |  |  | 8487(65.16) | 2876(65.38) | 2783(64.67) | 2828(66.35) |  |