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Table 2 Biochemical measurements and some descriptive variables according to KIDMED classification

From: The potential of the Mediterranean diet to improve metabolic control and body composition in youths with Type 1 Diabetes Mellitus

 

Whole group (n:285)

Poor (n:50)

Moderate (n:123)

Good (n:112)

p

Age (years)

13.7±3.63

14.1±3.26

13.7±3.45

13.6±3.99

0.734

Insulin treatment

 Insulin injection (n:240)

%84.2

%92.0

%91.9

%72.3

<0.01*

 Insulin pump (n:45)

%15.8

%8.0

%8.1

%27.7

 

Sensor use

 Yes (n:81)

%28.4

%12.0

%25.2

%39.3

<0.01*

 No (n:204)

%71.6

%88

%74.8

%60.7

 

 Insulin dose (units/kg)

0.9±0,28

1.1±0.28a

0.9±0.27b

0.8±0.27b

<0.01*

Metabolic control

 Good (n:91)

%31.9

%6.0

%17.9

%58.9

<0.01*

 Moderate (n:125)

%43.9

%28.0

%58.5

%34.8

 

 Bad (n:69)

%24.2

%66.0

%23.6

%6.3

 

 HbA1c

7.9±1.53

9.49±1.56a

8.1±1.26b

7.1±1.19c

<0.01*

 Time in range (TIR) (%)

73.9±16.63 (n:81)

56.3±21.26 (n:6)a

65.6±17.65 (n:31)a

81.5±9.69 (n:44)b

<0.01*

TIR classification

 > 70%

%49.4 (n:40)

%33.3 (n:2)

%29.0 (n:9)

%65.9 (n:29)

<0.01*

 <70%

%50.6 (n:41)

%66.7 (n;4)

%71.0 (n:22)

%34.1 (n:15)

 

 TC (mg/dL)

159.1±37.21

168.4±35.37a

162.1±37.15a,b

151.7±37.00b

<0.01*

 LDL- C (mg/dL)

93.6±27.62

94.3±26.82

97.4±26.62

89.4±28.69

0.093

 HDL- C (mg/dL)

60.9±17.79

62.8±24.40

59.6±16.49

61.4±15.63

0.508

 TG (mg/dL)

103.0±56.23

123.1±70.4a

104.9±50.2a,b

91.9±53.16b

<0.01*

 AST (U/L)

18.0±8.11

18.5±7.24

17.7±8.49

18.2±8.10

0.810

 ALT (U/L)

15.4±8.46

18.2±12.77a

14.2±7.37b

15.5±6.82a, b

<0.01*

Complications

 Yes (n:12)

%4.2

%8.0

%4.9

%1.8

0.170

 No (n:273)

%95.8

%92.0

%95.1

%98.2

 

Comorbidity

 Yes (n:23)

%8.1

%6.0

%7.3

%9.8

0.655

 No (n:262)

%91.9

%94.0

%92.7

%90.2

 

Dyslipidemia

 Yes (n:124)

%43.5

%56.0

%52.0

%28.6

0.000*

 No (n:161)

%56.5

%44.0

%48.0

%71.4

 

Pubertal situation

 Prepubertal (n:78)

%27.4

%20.0

%27.6

%30.4

0.392

 Pubertal (n:207)

%72.6

%80.0

%72.4

%69.6

 
  1. Categorical variables represented as (%). χ2: Chi squared. Significance set at p-value< 0.05
  2. TC Total cholesterol, LDL-C LDL- cholesterol, HDL-C HDL- cholesterol, AST Aspartate aminotransferase, ALT Alanine transaminase, TG Triglyceride
  3. * indicates statistical significance
  4. a,b,cindicate a significant difference according to Anova result