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Table 2 Associations between thyroid hormone sensitivity and PCOS

From: Correlation between thyroid hormone sensitivity and the risk of polycystic ovary syndrome

  

Model 1

 

Model 2

 

Model 3

 

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

FT3/FT4

(Quartile)

Q1

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 
 

Q2

2.48(1.48, 4.14)

<0.001

0.66(0.25,1.76)

0.406

0.80(0.28,2.30)

0.684

 

Q3

3.09(1.80, 5.31)

<0.001

0.73(0.24,2.24)

0.580

0.71(0.21,2.45)

0.590

 

Q4

6.01 (3.22, 11.21)

<0.001

0.90(0.31,2.61)

0.841

0.73(0.23,2.33)

0.590

 

P value for trend

<0.001

 

0.846

 

0.939

TT4RI

(Quartile)

Q1

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 
 

Q2

0.94(0.56,1.56)

0.798

0.24(0.08,0.72)

0.010

0.27(0.09,0.82)

0.022

 

Q3

1.15(0.68,1.94)

0.600

0.89(0.31,2.53)

0.822

0.92(0.30,2.79)

0.877

 

Q4

4.22(2.15,8.31)

<0.001

2.88(0.86,9.70)

0.087

2.73(0.75,9.98)

0.129

 

P value for trend

<0.001

 

0.002

 

0.007

TSHI

(Quartile)

Q1

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 
 

Q2

1.36(0.82,2.25)

0.238

0.96(0.35,2.62)

0.937

0.81(0.28,2.38)

0.706

 

Q3

1.75(1.04,2.96)

0.036

1.57(0.57,4.30)

0.384

1.46(0.50,4.27)

0.495

 

Q4

4.52(2.38,8.57)

<0.001

6.24(1.83,21.20)

0.003

5.35(1.48,19.37)

0.011

 

P value for trend

<0.001

 

0.016

 

0.036

TFQI

(Quartile)

Q1

1.00 (Reference)

 

1.00 (Reference)

 

1.00 (Reference)

 
 

Q2

1.17(0.71,1.93)

0.544

1.22(0.46,3.26)

0.689

1.11(0.39,3.16)

0.849

 

Q3

2.30(1.32,4.00)

0.003

4.47(1.44,13.92)

0.010

3.57(1.08,11.87)

0.038

 

Q4

3.40(1.87,6.18)

<0.001

5.49(1.62,18.61)

0.006

4.90(1.38,17.38)

0.014

 

P value for trend

<0.001

 

0.007

 

0.025

  1. Logistic regression models: Model 1 is adjusted for age; model 2 is adjusted for age and BMI; model 3 is adjusted for age, BMI, Hypertension, FPG ≥ 7.0, dyslipidemia
  2. Hypertension was defined as SBP ≥ 140mmHg or DBP ≥ 90mmHg; Dyslipidemia was defined as TG ≥ 1.7 mmol/L or TC ≥ 5.72 mmol/L or LDL ≥ 3.1 mmol/L or HDL ≤ 0.94 mmol/L
  3. Abbreviations: OR: odds ratio