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Table 2 Comparison of biochemical laboratory data

From: Identification of novel risk factors for postoperative severe hypocalcemia in patients with primary hyperparathyroidism undergoing parathyroidectomy: a case control study

Variable

All patients (n = 46)

SH group (n = 15)

Non-SH group (n = 31)

P value

Postoperative serum Ca (mmol/L, x ± s)

1.97 ± 0.17

1.77 ± 0.05

2.07 ± 0.11

 < 0.001*

Preoperative serum Ca (mmol/L, x ± s)

2.85 ± 0.32

2.71 ± 0.22

2.93 ± 0.34

0.012*

Decrease of serum Ca (mmol/L, x ± s)

0.88 ± 0.33

0.94 ± 0.23

0.85 ± 0.37

0.362

Percentage decrease of serum Ca (%, x ± s)

30.11 ± 9.03

34.07 ± 5.92

28.19 ± 9.71

0.037*

iPTH [pg/mL, M(Q1, Q3)]

461.7(174.8,887.7)

802.4(247.9,1282)

363(171.9,619.8)

0.038*

Serum P [mmol/L, M(Q1, Q3)]

0.66(0.57,0.81)

0.55(0.48,0.6)

0.72(0.59,0.88)

< 0.001*

Serum Ca/P (x ± s)

4.37 ± 1.20

5.00 ± 0.99

4.07 ± 1.19

0.012*

Urine Ca [mmol/24 h, M(Q1, Q3)]

3.77(2.99,5.30)

3.45(2.42,4.65)

3.92(3.15,5.61)

0.182

Urine P [mmol/24 h, M(Q1, Q3)]

9.94(6.37,13.36)

10.39(8.09,12.42)

9.42(6.08,13.54)

0.535

tP1NP [ng/mL, M(Q1, Q3)]

144.6(73.2,310.7)

257(146.8,549.3)

104.2(66.57,251)

0.007*

βCTX [ng/mL, M(Q1, Q3)]

1.30(0.59,1.97)

1.82(0.89,2.29)

1.01(0.57,1.82)

0.185

OC [ng/mL, M(Q1, Q3)]

106.5(33.3,161.9)

156.5(96.7,238)

58.2(29.9,141.3)

0.013*

25-(OH)-VD3 [ng/mL, M(Q1, Q3)]

9.02(6.9,13.7)

8.5(5.44,12.18)

9.71(7.91,14.6)

0.156

ALP [U/L, M(Q1, Q3)]

167(86,332)

296(209,553)

117(80,231)

0.002*

Serum creatinine [μmol/L, M(Q1, Q3)]

52(42,64)

45(35,63)

55(43,76)

0.125

BUN [mmol/L, M(Q1, Q3)]

4.05(3.2,5.225)

4(2.8,5.3)

4.1(3.6,5.2)

0.392

Serum uric acid (μmol/L, x ± s)

308.2 ± 89.1

314.53 ± 90.5

305.06 ± 89.71

0.739

  1. Serum Ca serum calcium, iPTH intact parathyroid hormone, serum P serum phosphorus, serum Ca/P preoperative serum calcium/serum phosphorus, urine Ca urine calcium, urine P urine phosphorus, tP1NP total procollagen type 1 intact N-terminal propeptide, βCTX β type 1 cross linked C-terminal telopeptide collagen, OC Osteocalcin, 25-(OH)-VD3 25-hydroxyvitamin D3, ALP Alkaline phosphatase, BUN Blood urea nitrogen
  2. * P < 0.05. SH group, patients with severe hypocalcemia after parathyroidectomy; non-SH group, patients without severe hypocalcemia after parathyroidectomy