Table 1 A comparative review of biochemical and inflammatory parameters and non-invasive scores between groups defined by ultrasound NAFLD severity grades
Characteristics | Grade 1 of liver steatosis (n = 89) | Grade 2 of liver steatosis (n = 55) | Grade 3 of liver steatosis (n = 40) | F | P |
|---|---|---|---|---|---|
BMI (kg/m2 ) | 25.61 ± 2.13 | 26.50 ± 1.83 | 27.67 ± 1.62ab | 6.049 | 0.003 |
WC (cm) | 90.43 ± 7.75 | 102.12 ± 7.66 | 102.21 ± 8.01ab | 94.200 | 0.000 |
HbA1c (%) | 7.55 ± 0.80 | 7.47 ± 0.53 | 7.47 ± 0.53 | 0.225 | 0.799 |
C-peptide (ng/ml) | 2.43 ± 0.58 | 4.13 ± 1.20 | 4.99 ± 0.61ab | 48.9 | 0.000 |
FPG (mmol/l) | 7.67 ± 1.23 | 6.41 ± 1.00 | 7.40 ± 0.63ab | 4.49 | 0.009 |
Platelet count(*109 /L) | 132 ± 43 | 144 ± 29 | 138 ± 38 | 7.431 | 0.099 |
ALT (U/L) | 24.70 ± 10.36 | 32.33 ± 11.82 | 54.55 ± 4.42ab | 18.05 | 0.000 |
AST (U/L) | 20.91 ± 3.61 | 19.05 ± 2.90 | 31.20 ± 3.64 | 0.834 | 0.438 |
γGT (U/L) | 22 ± 13 | 69 ± 20 | 122 ± 31 | 5.833 | 0.001 |
25(OH)D (ng/ml) | 35.69 ± 6.10 | 26.70 ± 3.10a | 14.53 ± 6.26ab | 7.17 | 0.001 |
PTH (pg/ml) | 37.67 ± 11.23 | 36.41 ± 14.00 | 37.40 ± 10.63 | 4.99 | 0.339 |
TC (mmol/l) | 6.63 ± 1.39 | 7.67 ± 1.23 | 7.67 ± 1.23ab | 4.208 | 0.018 |
TG (mmol/l) | 2.61 ± 0.71 | 2.48 ± 0.69 | 2.54 ± 0.62 | 0.411 | 0.664 |
HDL (mmol/l) | 1.38 ± 0.28 | 1.72 ± 0.39 | 1.66 ± 0.38ab | 9.800 | 0.000 |
LDL (mmol/l) | 3.84 ± 0.80 | 3.59 ± 0.69 | 3.73 ± 0.99 | 1.077 | 0.345 |
FLI | 57.74 ± 17.30 | 75.89 ± 9.65 | 89.86 ± 9.56ab | 5.286 | 0.007 |
FIB−4 | 1.67 ± 0.44 | 1.95 ± 0.99 | 2.46 ± 0.23ab | 4.206 | 0.018 |
lumbar spine bone density (g/cm2) | 0.99 ± 0.44 | 0.87 ± 0.61 | 0.75 ± 0.59ab | 3.734 | 0.006 |