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Table 2 Multivariate logistic regression analysis of factors associated with NAFLD in T2DM patients

From: Relationship between non-alcoholic fatty liver and progressive fibrosis and serum 25-hydroxy vitamin D in patients with type 2 diabetes mellitus

Covariate

Univariate analysis

Multivariate analysis

OR

95% CI

P

OR

95% CI

P

Age (years)

1.02

0.99–1.07

< 0.001

0.93

0.89–0.95

< 0.001

Sex

      

 Male

      

 Female

0.68

0.55–0.87

0.465

   

BMI (kg/m2 )

1.12

1.02–1.14

0.004

1.04

1.00-1.07

0.007

WC (cm)

1.13

1.07–1.15

0.038

0.83

0.79–0.85

0.344

HbA1C(%)

0.93

0.88–0.97

0.067

   

C-peptide (ng/ml)

0.73

0.69–0.78

0.694

   

FPG(mmol/l)

0.67

0.61–0.73

0.072

   

ALT(U/L)

0.66

0.62–0.70

0.029

   

AST(U/L)

0.73

0.68–0.76

0.018

   

25(OH)D(ng/ml)

1.17

1.14–1.23

0.003

1.26

1.22–1.29

0.001

PTH(pg/ml)

0.13

0.07–0.16

0.562

   

TC(mmol/l)

0.46

0.42–0.49

0.849

   

TG(mmol/l)

0.69

0.63–0.73

0.712

   

HDL-C(mmol/l)

0.34

0.30–0.37

0.088

   

LDL-C(mmol/l)

1.28

0.24–0.33

0.672

   

FLI

1.18

1.14–1.22

0.012

0.74

0.71–0.77

0.027

FIB-4

1.23

1.19–1.27

0.025

1.09

1.06–1.12

0.011

  1. BMI body mass index, WC waist circumference, HbA1c glycated hemoglobin, 25(OH)D 25-hydroxy vitamin D, FPG fasting plasma glucose, ALT alanine transaminase, AST aspartate aminotransferase, γGT gamma-glutamyl transferase, PTH Parathyroid Hormone, TC total cholesterol TG triglycerides, HDL high density lipoprotein, LDL low density lipoprotein, FLI Fatty liver index score, FIB-4 Fibrosis-4 score
  2. a indicates P<0.05, compare with hepatic steatosis grade 1; b indicates P<0.05, compare with hepatic steatosis grade 2
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BMC Endocrine Disorders

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