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Fig. 7 | BMC Endocrine Disorders

Fig. 7

From: Sex hormones differently regulate lipid metabolism genes in primary human hepatocytes

Fig. 7

Influence of progesterone on mRNA expression levels of primary human hepatocytes (PHHs) of different sex. PHHs were isolated from liver tissues of female (A, C, E) and male (B, D. F) donors, cultured with PHH starving medium supplemented with 70 nM progesterone for up to 72 h and mRNA expression levels of A, B ATP-binding cassette, sub-family A, member 1 (ABCA1), C, D apolipoprotein A-V (APOA5) and E, F peroxisome proliferator-activated receptor alpha (PPARA) were analyzed by RT-qPCR. Individual fold change values are displayed as dots and cubes, bar graphs display means ± SEM, n = 7 per sex, p < 0.05 (*)

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