Serum ferritin level and associated factors among uncontrolled adult type II diabetic follow-up patients: comparative based cross-sectional study

Table 5 Bivariate and multivariate logistic regression showing factors associated with elevated serum ferritin levels among T2DM patients at SPHMMC, Addis Ababa, Ethiopia, 2024 (n = 104)

Tested parameters	Category	Serum ferritin >200 ng/ml		Bivariate analysis		Multivariate analysis
Tested parameters	Category	Yes (n=54)	No (n=50)	COR(95% CI)	P	AOR(95% CI)	P
Age (yrs)^a	18-33	10	5	1
	34-49	23	21	0.55(0.16-1.87)	0.336	0.43(0.06-2.94)	0.389
	50-65	21	24	0.44(0.13-1.49)	0.185	0.19(0.02-1.50)	0.115
Sex^a	Male	33	15	1
Sex^a	Female	21	35	0.27(0.12-0.62)	0.002	0.16(0.05-0.57)	0.004
Educational levels^b	No formal	5	6	1
	Primary	15	14	1.29(0.32-5.18)	0.724
	Secondary	22	16	1.65(0.43-6.37)	0.467
	Higher	12	14	1.03(0.25-4.24)	0.969
BMI(kg/m²)^a	<18.5	3	3	1
	18.5-24.9	13	24	0.54(0.09-3.08)	0.489	0.12(0.01-1.46)	0.097
	25-29.9	28	21	1.33(0.24-7.28)	0.740	0.44(0.04-4.42)	0.485
	≥30	10	2	5.0(0.55-45.39)	0.153	2.27(0.09-57.2)	0.618
SBP(mmHg)^a	<120	8	13	1
	120-139	24	24	1.63(0.57-4.63)	0.363	1.48(0.33-6.73)	0.610
	≥140	22	13	2.75(0.90-8.40)	0.076	1.56(0.25-9.81)	0.637
DBP(mmHg)^a	<80	15	19	1
	80-89	21	22	1.21(0.49-2.98)	0.680	0.50(0.12-2.23)	0.365
	≥90	18	9	2.53(0.89-7.23)	0.082	0.48(0.08-2.89)	0.425
Duration on DM (yrs)^a	<5	12	8	1
	5-10	17	23	0.49(0.17-1.47)	0.204	0.80(0.16-4.06)	0.788
	>10	25	19	0.88(0.30-2.57)	0.811	0.35(0.05-2.30)	0.276
Mode of therapy ^a	OHA	41	27	1
Mode of therapy ^a	Insulin	13	23	0.37(0.16-0.86)	0.020	0.26(0.07-0.95)	0.042
HbA1c (%)^a	M±SD	8.8 ±1.9	7.1± 1.0	2.12(1.50-3.01)	<0.001	3.67(1.50-8.98)	0.004
FBs (mg/dl)^a	M±SD	176.4±59.2	136.1±42.4	1.02(1.01-1.03)	<0.001	0.99(0.97-1.01)	0.233
Serum iron (ug/dl)^a	M±SD	142.8±33.9	114.2±32.6	1.03(1.01-1.04)	<0.001	1.02(1.01-1.04)	0.017

1-Indicates the reference group; COR = crude odds ratio; AOR = adjusted odds ratio; CI = confidence interval; M = mean; SD = Standard Deviation; p-value significant at 0.05 level (2-tailed); ^a=variables exported to multivariate logistic regression; ^b=variables not exported to multivariate logistic regression model

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