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Table 1 Clinical characteristics of diabetes patients who tested positive or negative for H. pylori infection*

From: Association of Helicobacter pylori infection with complications of diabetes: a single-center retrospective study

Characteristic

Overall

(n = 960)

H pylori (+)

(n = 481)

H pylori (−)

(n = 479)

P value**

Age, years

58.84 ± 10.32

58.56 ± 10.66

59.11 ± 9.98

0.410

Gender

 Male

 Female

594 (61.9)

366 (38.1)

311 (64.7)

170 (35.3)

283 (59.1)

196 (40.9)

0.075

BMI, kg/m2

24.65 ± 3.33

24.59 ± 3.29

24.71 ± 3.38

0.601

Smoking history

336 (35.0)

182 (37.8)

154 (32.2)

0.065

Alcohol intake

211 (22.0)

117 (24.3)

94 (19.6)

0.079

Hypertension

491 (51.1)

249 (51.8)

242 (50.5)

0.700

Known diabetes duration, years

9.65 ± 7.34

9.54 ± 7.29

9.76 ± 7.41

0.642

HbA1c, %

8.81 ± 2.12

8.92 ± 2.13

8.70 ± 2.11

0.104

TC, mmol/L

4.49 ± 1.17

4.50 ± 1.16

4.48 ± 1.18

0.843

TG, mmol/L

1.55 [1.06, 2.27]

1.55 [1.07, 2.34]

1.54 [1.04, 2.20]

0.495

HDL-C, mmol/L

1.09 ± 0.38

1.09 ± 0.45

1.10 ± 0.29

0.880

LDL-C, mmol/L

2.51 ± 0.87

2.49 ± 0.83

2.53 ± 0.90

0.498

Calcium, mmol/L

2.25 ± 0.11

2.25 ± 0.10

2.24 ± 0.11

0.071

Gastroscopy

708 (73.8)

335 (69.6)

373 (77.9)

 

Endoscopic findings

 Atrophic gastritis

 Peptic ulcer

 Othersa

 No gastroscopy done

116 (12.1)

98 (10.2)

494 (51.5)

252 (26.3)

51(10.6)

70 (14.6)

214 (44.5)

146 (30.4)

65 (13.6)

28 (5.8)

280 (58.5)

106 (22.1)

< 0.001

Osteoporosis

149 (15.5)

70 (14.6)

79 (16.5)

0.407

Retinopathy

250 (26.0)

131 (27.2)

119 (24.8)

0.399

Nephropathy

147 (15.3)

85 (17.7)

62 (12.9)

0.042

Peripheral neuropathy

715 (74.5)

352 (73.2)

363 (75.8)

0.355

PVD

607 (63.2)

303 (63.0)

304 (63.5)

0.880

  1. Abbreviations BMI, body mass index; HbA1c, glycated haemoglobin A1c; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; PVD, peripheral vascular disease; H. pylori, Helicobacter pylori
  2. *Data are presented as number (percentage), mean ± standard deviation, or median [interquartile range]
  3. **Calculated using the independent samples t-test, χ2 test, or Mann-Whitney U test. Bold font indicates statistical significance
  4. aOthers include nodular gastritis, gastric erosion, and gastric polyp