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Table 1 General characteristics of studies included in meta-analysis

From: Predictive role of neutrophil-to-lymphocyte ratio in metabolic syndrome: Meta-analysis of 70,937 individuals

References

Time

Study design

Country

Sample size

Mean age

(year)

Gender, M/F

Diagnostic criteria

Experiment group

Control group

AHQR/NOS (stars/ scores)

Buyukkaya E [9]

2014

Case-control

Turkey

141

47.5 ± 11.7

76/65

NCEP-ATP3

MS

Non-MS

8/9

Surendar J [10]

2016

Cross-sectional

India

754

48.2 ± 12.2

420/334

NCEP-ATP3

MS

Non-MS

10/11

Battaglia S [11]

2020

Cross-sectional

Italy

771

56.34 ± 13.63

391/380

IDF

MS

Non-MS

11/11

Kaya T [12]

2017

Cross-sectional

Turkey

261

56.7 ± 10.5

113/148

NCEP-ATP3

MS

Non-MS

11/11

Kim JH [13]

2017

Cross-sectional

Korea

1,007

48.3 ± 9.7

659/348

NCEP-ATP3

MS

Non-MS

10/11

Liu CC [14]

2019

Retrospective cohort

Tai Wan

34,013

50.46 ± 11.09

23,877/10,136

NCEP-ATP3

MS

Non-MS

7/9

Tang K [15]

2017

Retrospective cohort

China

513

52.27 ± 10.95

294/219

NCEP-ATP3

MS

Non-MS

7/9

Wang PB [16]

2022

Cross-sectional

China

7,420

53.71 ± 8.68

3,359/4,061

IDF

MS

Non-MS

10/11

Yasar Z [17]

2015

Case-control

Turkey

140

65.16 ± 10.3

103/37

IDF

MS

Non-MS

8/9

Zubiaga L [18]

2020

Retrospective cohort

Spain

200

43.9 ± 10.9

150/50

NCEP-ATP3

MS

Non-MS

8/9

Li N [19]

2023

Cross-sectional

China

7,726

48.40 ± 10.73

4,397/3,329

Chinese Diabetes Society criteria

MS

Non-MS

10/11

Mohan M [20]

2021

Cross-sectional

India

210

57 ± 9.545

108/102

NCEP-ATP3

MS

Non-MS

10/11

Bahadir A [21]

2015

Cross-sectional

Turkey

1,267

37.7 ± 10.8

109/1,068

NCEP-ATP3

MS

Non-MS

11/11

Najafzadeh MJ [22]

2023

Cross-sectional

Iran

1,033

45.16 ± 13.88

373/660

NCEP-ATP3

MS

Non-MS

10/11

Omrani-Nava V [23]

2023

Retrospective cohort

Iran

1,930

35–70

842/1,088

NCEP-ATP3

MS

Non-MS

8/9

Ustuntas G [24]

2021

Case-control

Turkey

219

70.5 ± 5.4

155/64

NCEP-ATP3

MS

Non-MS

8/9

Al-Sarraf IAK [25]

2018

cross-sectional

Jordan

87

42.7 ± 1.9

41/46

IDF

MS

Non-MS

10/11

AbuZayed R [26]

2019

Cross-sectional

Jordan

88

49.86 ±

11.34

24/64

IDF

MS

Non-MS

10/11

Horan AA [27]

2019

Cross-sectional

Jordan

88

49.78 ± 10.22

24/64

IDF

MS

Non-MS

10/11

Mauss D [28]

2021

Retrospective cohort

Germany

689

45.5 ± 9.8

620/69

AHA/NHLBI 2009

MS

Non-MS

7/9

Song PY [29]

2022

Cross-sectional

China

860

61.45 ± 12.5

524/336

IDF

MS

Non-MS

10/11

Abdel-Moneim A [33]

2019

Case-control

Egypt

250

44.08 ± 8.41

125/125

NCEP-ATP3

MS

Non-MS

8/9

Lin HY [34]

2021

Retrospective cohort

China

1,542

44.8 ± 12.6

1,056/486

Chinese Diabetes Society criteria

High NLR

Low NLR

9/9

Fang Q [35]

2018

Case-control

China

3,080

50.75 ± 10.36

0/3,080

AHA/NHLBI 2005

High NLR

Low NLR

8/9

Conteduca V [36]

2018

Retrospective cohort

Italy

336

75

336/0

NCEP-ATP3

High NLR

Low NLR

9/9

Meng G [37]

2017

Cross-sectional

China

6,312

60.28

3,821/2,491

AHA/NHLBI 2009

High NLR

Low NLR

10/11

  1. M male, F female, NOS Newcastle-Ottawa Scale, NLR neutrophil-to-lymphocyte ratio, MS metabolic syndrome, NCEP ATP III National Cholesterol Education Program Adult Treatment Panel III, AHRQ Agency for Healthcare Research and Quality, AHA/NHLBI American Heart Association/National Heart, Lung, and Blood Institute, IDF International Diabetes Federation