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Table 3 Clinical outcomes before and after Diabetes Alliance integrated care in general practices

From: Spillover effects from a type 2 diabetes integrated model of care in 22,706 Australians: an open cohort stepped wedge trial

  

Before program

After program

  

Clinical outcome

N

Mean estimate

(95% CI)1

Mean estimate

(95% CI)1

Difference in means (95% CI)2

P-value

Weight (kg)

14,882

90.19

(89.85, 90.53)

88.81

(88.47, 89.16)

-1.38

(-1.38, -1.87)

< 0.0001

Waist circum. (cm)

7,113

109.80

(109.40, 110.20)

109.50

(109.10, 109.90)

-0.28

(-0.59, 0.03)

0.0764

BMI (kg/m2)

13,111

32.24

(32.13, 32.35)

31.80

(31.69, 31.92)

-0.44

(-0.44, -0.44)

< 0.0001

Systolic BP (mmHg)

17,963

135.80

(135.60, 136.00)

134.70

(134.50, 135.00)

-1.12

(-1.33, -0.91)

< 0.0001

Diastolic BP

(mmHg)

17,966

77.07

(76.94, 77.21)

75.90

(75.74, 76.06)

-1.18

(-1.30, -1.05)

< 0.0001

HbA1c (%)

15,144

6.84

(6.82, 6.86)

6.81

(6.79, 6.83)

-0.03

(-0.03, -0.03)

0.0021

HbA1c

(mmol/mol)

15,144

50.70

(50.50, 50.90)

50.43

(50.20, 50.66)

-0.27

(-0.27, -0.27)

0.0041

ACR (mg/mmol)

11,081

1.77

(1.72, 1.82)

1.84

(1.78, 1.90)

0.07

(0.07, 0.07)

0.0072

Total chol.

(mmol/L)

14,878

4.32

(4.30, 4.34)

4.22

(4.20, 4.24)

-0.11

(-0.10, -0.10)

< 0.0001

LDL

(mmol/L)

12,432

2.17

(2.16, 2.19)

2.07

(2.05, 2.09)

-0.10

(-0.10, -0.10)

< 0.0001

HDL

(mmol/L)

12,926

1.15

(1.15, 1.16)

1.15

(1.14, 1.16)

-0.01

(-0.01, -0.01)

0.0494

Triglycerides

(mmol/L)

14,803

1.77

(1.76,1.79)

1.76

(1.74,1.77)

-0.02

(-0.02, -0.02)

0.0078

Creatinine

(µmol/L)

16,072

82.60

(82.20, 83.00)

84.67

(84.22, 85.11)

2.07

(2.07, 2.08)

< 0.0001

  1. BP, blood pressure; chol, cholesterol; circum, circumference; cm, centimetre; kg, kilogram; L, litre; m, metre; mmHg, millimetre of mercury; mmol, millimole; µmol, micromole
  2. 1Weight, BMI, HbA1c (percentage and mmol/.mol), ACR, cholesterol, LDL, HDL, Triglycerides, and Creatinine were all log-transformed to meet normality assumptions
  3. 2Weight, BMI, HbA1c, ACR, cholesterol, LDL, HDL, Triglycerides, and Creatinine were back-transformed. Estimated difference only valid at the means (at higher reference values of the outcome the estimated difference will be greater, and at smaller reference values the difference will be smaller)
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BMC Endocrine Disorders

ISSN: 1472-6823

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