Cholesterol to saturated fat index (CSI), metabolic parameters and inflammatory factors among obese individuals

BMC Endocrine Disorders

Table 4 The odds of high metabolic and inflammatory parameters in second and third tertile of CSI versus first tertile in study population

CSI tertiles		OR-crude	95% Confidence Interval		P- value *	OR-adjusted	95% Confidence Interval		P- value **
CSI tertiles		OR-crude	Lower Bound	Upper Bound	P- value *	OR-adjusted	Lower Bound	Upper Bound	P- value **
1st (≤ 7.90) Ref
2nd (7.90–11.29)	SBP (mmHg)	1.01	0.98	1.05	0.37	1.02	0.26	1.06	0.26
	DBP (mmHg)	0.98	0.94	1.02	0.31	0.97	0.24	1.02	0.24
	Glucose (mg/dl)	1.02	1.01	1.08	0.01	1.03	1.01	1.08	0.02
	Cholesterol (mg/dl)	1.01	0.98	1.04	0.37	0.99	0.22	1.01	0.22
	Triglyceride (mg/dl)	0.99	0.99	1.01	0.35	0.99	0.89	1.01	0.89
	HDL (mg/dl)	0.99	0.95	1.03	0.56	0.99	0.75	1.04	0.75
	LDL (mg/dl)	0.98	0.95	1.01	0.26	0.99	0.85	1.04	0.65
	Insulin (mIU/l)	0.98	0.96	1.01	0.30	0.95	0.87	1.06	0.58
	HOMA-IR	0.97	0.86	1.08	0.61	0.87	0.74	1.02	0.08
	Hs-CRP (mg/dl)	1.01	0.86	1.08	0.12	1.01	0.98	1.06	0.09
	IL-6 (mg/dl)	0.68	0.59	1.01	0.78	0.99	0.58	1.04	0.85
3rd (≥ 11.29)	SBP (mmHg)	1.01	0.98	1.04	0.44	1.01	0.58	1.05	0.59
	DBP (mmHg)	0.99	0.96	1.04	0.92	1.00	0.99	1.05	0.99
	Glucose (mg/dl)	1.01	0.99	1.04	0.22	1.01	0.47	1.04	0.47
	Cholesterol (mg/dl)	1.01	0.98	1.04	0.46	0.99	0.98	1.09	0.32
	Triglyceride (mg/dl)	0.99	0.99	1.01	0.54	1.01	0.52	1.01	0.52
	HDL (mg/dl)	0.97	0.93	1.01	0.19	1.01	0.88	1.05	0.88
	LDL (mg/dl)	0.98	0.95	1.01	0.17	0.98	0.89	1.03	0.72
	Insulin (mIU/l)	1.01	0.99	1.03	0.47	0.97	0.17	1.01	0.17
	HOMA-IR	1.04	0.95	1.14	0.37	0.93	0.80	1.08	0.36
	Hs-CRP (mg/dl)	1.01	1.01	1.09	0.02	1.02	1.01	1.09	0.01
	IL-6 (mg/dl)	0.98	0.85	1.02	0.12	0.98	0.85	1.02	0.12

CSI Cholesterol to saturated fat index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, HDL-C High Density Lipoprotein Cholesterol, LDL-C Low Density Lipoprotein Cholesterol, HOMA-IR Homeostatic model assessment of insulin resistance, hs-CRP high sensitive C reactive protein, IL-6 Interleukin 6; *P-values of crude model of multinomial logistic regression; ** P-values of adjusted model of multinomial logistic regression for age, sex, BMI, physical activity and energy intake

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