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Fig. 6 | BMC Endocrine Disorders

Fig. 6

From: FPS-ZM1 attenuates the deposition of lipid in the liver of diabetic mice by sterol regulatory element binding protein-1c

Fig. 6

The mechanism of AGEs involving in lipids disorder via SREBP-1c. Notes: The interaction between AGEs and its receptor, RAGE, initiates phosphorylation events involving p65 nfκb and p38 MAPK. The phosphorylation of these signaling molecules contributes to subsequent processing of the SREBP-1c precursor into its mature form, thereby culminating in dysregulation of lipid metabolism

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