Skip to main content

Table 4 The association between live births with CMD and its components

From: Associations between live birth and cardiometabolic disease in Southwest Chinese women

Diseases

Crude

P-value

Model 1a

P-value

Model 2b

P-value

PR (95% CI)

PR (95% CI)

PR (95% CI)

Hypertension

      

 Live birth = 1

1.00

 

1.00

1.00

1.00

 

 Live birth = 2

1.12 (0.82–1.52)

0.472

0.92 (0.66–1.26)

0.593

0.91 (0.66–1.27)

0.587

 Live birth ≥ 3

2.77 (2.03–3.79)

< 0.001

0.99 (0.67–1.46)

0.957

1.04 (0.70–1.54)

0.858

 Pfor trend

 

< 0.001

 

0.905

 

0.919

T2DM

      

 Live birth = 1

1.00

1.00

1.00

1.00

1.00

 

 Live birth = 2

0.70 (0.43–1.17)

0.172

0.56 (0.33–0.95)

0.030c

0.64 (0.38–1.10)

0.105

 Live birth ≥ 3

1.03 (0.62–1.71)

0.919

0.35 (0.18–0.68)

0.002c

0.48 (0.25–0.95)

0.034c

 Pfor trend

 

0.981

 

0.001c

 

0.028c

Obesity

      

 Live birth = 1

1.00

1.00

1.00

1.00

1.00

 

 Live birth = 2

3.34 (2.39–4.65)

< 0.001

3.43 (2.45–4.79)

< 0.001

3.32 (2.36–4.69)

< 0.001

 Live birth ≥ 3

4.80 (3.39–6.81)

< 0.001

5.59 (3.74–8.35)

< 0.001

5.73 (3.79–8.68)

< 0.001

 Pfor trend

 

< 0.001

 

< 0.001

 

< 0.001

Dyslipidemia

      

 Live birth = 1

1.00

1.00

1.00

1.00

1.00

 

 Live birth = 2

1.98 (1.47–2.67)

< 0.001

1.81 (1.34–2.45)

< 0.001

1.75 (1.29–2.39)

< 0.001

 Live birth ≥ 3

3.52 (2.57–4.82)

< 0.001

2.04 (1.41–2.94)

< 0.001

2.02 (1.38–2.94)

< 0.001

 Pfor trend

 

< 0.001

 

< 0.001

 

< 0.001

MetS

      

 Live birth = 1

1.00

1.00

1.00

1.00

1.00

 

 Live birth = 2

1.16 (0.79–1.70)

0.442

0.99 (0.67–1.46)

0.949

1.27 (0.83–1.95)

0.267

 Live birth ≥ 3

1.91 (1.30–2.81)

0.001

0.81 (0.50–1.30)

0.386

1.64 (0.89–2.43)

0.128

 Pfor trend

 

0.001

 

0.410

 

0.124

CMD

      

 Live birth = 1

1.00

1.00

1.00

1.00

1.00

 

 Live birth = 2

2.13 (1.63–2.78)

< 0.001

1.93 (1.47–2.54)

< 0.001

1.91 (1.44–2.54)

< 0.001

 Live birth ≥ 3

4.38 (3.17–6.06)

< 0.001

2.12 (1.47–3.06)

< 0.001

2.15 (1.46–3.15)

< 0.001

 Pfor trend

 

< 0.001

 

< 0.001

 

0.001

  1. Abbreviations: OR Odds ratio, CI Confidence interval, T2DM Type 2 diabetes mellitus, MetS Metabolic syndrome, CMD Cardiometabolic disease
  2. Logistic regression analysis was utilized in those models
  3. a Model 1 was adjusted by enrollment age (continuous variable)
  4. b Model 2 was adjusted by Model 1 + minority ethnicity, married, CVD family history, lower income, smoking, alcohol intake, number of miscarriages (continuous variable), and menopausal status among baseline variables
  5. c Likely exhibited over-adjustment, as the crude analysis failed to demonstrate statistical significance
Back to article page

BMC Endocrine Disorders

ISSN: 1472-6823

Contact us