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Table 2 Comparison of ATD-treated Graves’ disease patients who achieved remission versus patients who did not achieve remission

From: Efficacy of Anti-Thyroid Medications in Patients with Graves’ Disease

Variable

Remission

(n = 103)

No remission (n = 86)

P-value

Age (years), n, [Median (IQR)]

103,[39.0( 34.00, 50.00)]

86,[38.0( 31.00, 49.00)]

0.484^

Free T3 upon diagnosis(pmol/l), n, [Median (IQR)]

103,[9.2( 7.00, 15.80)]

82,[11.1( 6.40, 23.60)]

0.177^

Free T4 upon diagnosis(pmol/l), n, [Mean (SD)]

103,[25.8 ( 8.93 )]

86,[28.8 ( 10.82)]

0.038*

TSH receptor antibodies level up on diagnosis(IU/l), n, [Median (IQR)]

93,[5.1( 2.90, 10.70)]

73,[10.5( 4.20, 22.50)]

0.001^

Thyroid uptake on 99mTc-pertechnetate scan (%),n, [Median (IQR)]

79,[7.8( 3.77, 14.70)]

61,[10.5( 4.77, 21.50)]

0.061^

BMI (Kg/m2), n, Mean (SD)

103,[28.8 ( 5.88 )]

86,[ 29.4 ( 6.40 )]

0.485*

Duration of ATDs treatment (months), n, [Median (IQR)]

103,[29.0( 20.00, 42.00)]

86,[33.0( 23.00, 53.00)]

0.154^

Female patients, n (%)

84 ( 81.6 )

52 ( 60.5 )

0.001**

Male patients, n (%)

19 ( 18.4 )

34 ( 39.5 )

0.001**

Mild ophthalmopathy, n (%)

81 ( 84.4 )

48 ( 56.5 )

< 0.0001**

Moderate or severe ophthalmopathy, n (%)

15 ( 15.6 )

37$ ( 43.5 )

< 0.0001**

  1. IQR: interquartile range
  2. SD: standard deviation
  3. ATDs: anti-thyroid drugs
  4. * P value calculated using T -Test
  5. ^ P value calculated using Wilcoxon rank sum test
  6. ** P value calculated using Chi-square test
  7. $ This include 2 patients with severe ophthalmopathy and 35 patients with moderate ophthalmopathy