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Table 3 Comparison of Graves’ disease patients who experienced relapse after ATDs discontinuation versus patients who did not experience relapse

From: Efficacy of Anti-Thyroid Medications in Patients with Graves’ Disease

Variable

Relapse

(n = 35)

No relapse

(n = 68)

P-value

Age (years), n, [Median (IQR)]

35,[38.0( 33.00, 51.00)]

68,[39( 34.00, 49.50)]

0.826^

Free T3 upon diagnosis(pmol/l), n, [Median (IQR)]

35,[9.1( 5.80, 15.70)]

68,[9.4( 7.05, 16.60)]

0.526^

Free T4 upon diagnosis(pmol/l), n, [Mean (SD)]

35,[26.7 ( 8.21 )]

68,[25.4 ( 9.31 )]

0.495*

TSH receptor antibodies level up on diagnosis(IU/l), n, [Median (IQR)]

32,[5.0( 3.70, 10.90)]

61,[5.1( 2.50, 10.30)]

0.454^

Thyroid uptake on 99mTc-pertechnetate scan (%),n, [Median (IQR)]

30,[10.3( 5.19, 16.81)]

49,[6.0( 3.09, 12.38)]

0.030^

BMI (Kg/m2), n, Mean (SD)

35,[27.8 ( 6.38 )]

68,[29.3 ( 5.58 )

0.215*

Duration of ATDs treatment (months), n, [Median (IQR)]

35,[40.0( 29.00, 58.00)]

68,[25.0( 19.00, 32.50)]

< 0.0001^

Female patients, n (%)

30 ( 85.7 )

54 ( 79.4 )

0.435**

Male patients, n (%)

5 ( 14.3 )

14 ( 20.6 )

0.435**

Mild ophthalmopathy, n (%)

29 ( 87.9 )

52 ( 82.5 )

0.494**

Moderate ophthalmopathy, n (%)

4 ( 12.1 )

11 ( 17.5 )

0.494**

  1. IQR: interquartile range
  2. SD: standard deviation
  3. ATDs: anti-thyroid drugs
  4. * P value calculated using T -Test
  5. ^ P value calculated using Wilcoxon rank sum test
  6. ** P value calculated using Chi-square test