Table 1 Weighted characteristics of the study population based on different cut-off values of high-density lipoprotein cholesterol
Cholesterol (mmol/L) | Q1 | Q2 | Q3 | Q4 | P-value |
|---|---|---|---|---|---|
0.26 - 1.135 | 1.14 - 1.36 | 1.37 - 1.655 | 1.66 - 5.07 | ||
N | 6431 | 6989 | 7312 | 7352 | |
Age(years) | 37.67 ± 11.77 | 36.57 ± 12.01 | 36.30 ± 12.14 | 36.23 ± 12.02 | <0.001 |
Sex, n (%) | <0.001 | ||||
Male | 4232 (65.81%) | 3666 (52.45%) | 3091 (42.27%) | 2292 (31.18%) | |
Female | 2199 (34.19%) | 3323 (47.55%) | 4221 (57.73%) | 5060 (68.82%) | |
Race/ethnicity (%) | |||||
Non-Hispanic White | 59.56 | 58.27 | 59.62 | 63.76 | |
Non-Hispanic Black | 12.59 | 12.33 | 10.58 | 7.03 | |
Mexican American | 12.55 | 12.61 | 10.74 | 7.04 | |
Other race/ethnicity | 18.89 | 17.62 | 17.57 | 15.35 | |
Education level (%) | |||||
Less than high school | 18.67 | 13.62 | 11.79 | 9.24 | |
High school | 24.49 | 23.01 | 23.43 | 19.46 | |
More than high school | 56.92 | 62.47 | 64.51 | 71.34 | |
Moderate activities (%) | |||||
Yes | 66.14 | 67.83 | 75.09 | 75.36 | |
No | 33.95 | 33.17 | 24.91 | 24.40 | |
Body mass index (kg/m2) | 30.93 ± 8.15 | 28.35 ± 2.84 | 27.45 ± 5.52 | 26.43 ± 6.28 | <0.001 |
ALT(U/L, mean ± SD) | 28.99 ± 32.26 | 23.65 ± 19.39 | 21.15 ± 15.65 | 19.77 ± 17.43 | <0.001 |
ASL(U/L, mean ± SD) | 26.10 ± 19.23 | 24.04 ± 13.90 | 23.52 ± 14.48 | 24.49 ± 20.34 | <0.001 |
Blood urea nitrogen(mg/dL, mean ± SD) | 4.49 ± 1.75 | 4.40 ± 1.59 | 4.35 ± 1.67 | 4.22 ± 1.70 | <0.001 |
Creatinine(mg/dL, mean ± SD) | 80.28 ± 32.58 | 73.08 ± 27.38 | 72.54 ± 21.14 | 67.41 ± 14.26 | <0.001 |
Serum uric acid(umol/L, mean ± SD) | 344.01 ± 84.54 | 316.65 ± 81.46 | 295.97 ± 78.56 | 277.90 ± 78.34 | <0.001 |
Total calcium(mg/dL, mean ± SD) | 9.30 ± 0.35 | 9.36 ± 0.64 | 9.38 ± 0.53 | 9.36 ± 0.34 | <0.001 |
Serum phosphorus(mg/dL, mean ± SD) | 3.91 ± 0.60 | 3.70 ± 0.83 | 3.77 ± 0.75 | 3.85 ± 0.74 | <0.001 |
25(OH)D(umol/L, mean ± SD) | 60.27 ± 23.66 | 64.09 ± 25.32 | 65.63 ± 25.78 | 69.25 ± 28.24 | <0.001 |
Smoked at least 100 cigarettes in life（%） | <0.001 | ||||
Yes | 1091 (3.88%) | 2390 (8.51%) | 1740 (6.20%) | 1035 (3.69%) | |
No | 3020 (10.75%) | 7049 (25.09%) | 5589 (19.90%) | 6170 (21.97%) | |
Had at least 12 alcohol drinks/lifetime（%） | 0.165 | ||||
Yes | 2721 (74.88%) | 2473 (72.86%) | 2523 (72.79%) | 2607 (73.46%) | |
No | 911 (25.07%) | 921 (27.14%) | 943 (27.21%) | 940 (26.49%) | |
Diabetes（%） | <0.001 | ||||
Yes | 532 (8.86%) | 444 (6.80%) | 388 (5.75%) | 292 (4.26%) | |
No | 5384 (89.63%) | 6017 (92.13%) | 6302 (93.32%) | 6524 (95.09%) | |
Hypertension（%） | <0.001 | ||||
Yes | 1493 (26.51%) | 1383 (23.09%) | 1365 (21.83%) | 1324 (20.73%) | |
No | 4120 (73.17%) | 4596 (76.73%) | 4875 (77.96%) | 5053 (79.11%) | |