Table 1 Baseline characteristics of adults included in the final analysis according SII quartiles
Total | Total | Q1 | Q2 | Q3 | Q4 | P value |
|---|---|---|---|---|---|---|
Age [year] | 38.46(0.26) | 37.82(0.41) | 37.83(0.39) | 38.86(0.34) | 39.25(0.44) | 0.002 |
Sex | < 0.0001 | |||||
Male | 5603(50.06) | 1652(59.56) | 1452(53.62) | 1365(49.42) | 1134(41.44) | |
Female | 5589(49.94) | 1146(40.44) | 1346(46.38) | 1437(50.58) | 1660(58.56) | |
Race | < 0.0001 | |||||
Mexican American | 1735(15.5) | 372(10.09) | 454(11.12) | 443(10.35) | 466(11.17) | |
Non-Hispanic Black | 2308(20.62) | 926(19.40) | 537(10.11) | 422( 7.61) | 423( 7.79) | |
Non-Hispanic White | 3830(34.22) | 693(52.77) | 963(61.30) | 1064(64.48) | 1110(64.89) | |
Other Hispanic | 1185(10.59) | 237(6.70) | 296(7.58) | 336(8.00) | 316(7.71) | |
Other Race | 2134(19.07) | 570(11.04) | 548( 9.89) | 537( 9.56) | 479( 8.45) | |
Education level | 0.004 | |||||
Under high school | 657(5.87) | 164(4.16) | 193(4.24) | 164(3.83) | 136(3.13) | |
High school or equivalent | 4096(36.6) | 1043(33.17) | 970(29.08) | 1009(32.69) | 1074(34.94) | |
Above high school | 6437(57.52) | 1590(62.67) | 1635(66.68) | 1629(63.48) | 1583(61.93) | |
PIR | 0.27 | |||||
< 1.30 | 3815(34.11) | 888(22.86) | 980(25.35) | 938(23.29) | 1009(26.88) | |
1.30–3.49 | 3992(35.69) | 1014(35.33) | 1019(34.26) | 999(34.47) | 960(33.39) | |
> = 3.50 | 3377(30.19) | 892(41.81) | 798(40.39) | 865(42.24) | 822(39.74) | |
Smoke status | 0.01 | |||||
Never smoker | 6850(62.55) | 1740(61.19) | 1756(61.48) | 1736(60.24) | 1618(57.21) | |
Former smoker | 1747(15.95) | 416(18.80) | 462(20.28) | 415(17.96) | 454(18.92) | |
Now smoker | 2354(21.5) | 563(20.01) | 517(18.24) | 606(21.80) | 668(23.88) | |
Alcohol status | 0.03 | |||||
Never alcohol user | 1592(15.53) | 433(12.01) | 396(10.68) | 375(10.12) | 388(11.18) | |
Former alcohol user | 896(8.74) | 208(7.34) | 215(6.93) | 229(8.86) | 244(9.25) | |
Mild alcohol user | 3263(31.83) | 875(35.09) | 836(35.35) | 793(32.09) | 759(31.27) | |
Moderate alcohol user | 1855(18.09) | 418(18.67) | 469(21.02) | 489(21.66) | 479(19.39) | |
Heavy alcohol user | 2646(25.81) | 640(26.90) | 643(26.03) | 666(27.28) | 697(28.91) | |
Physical activity level | < 0.0001 | |||||
NMVPA (0 MET-mins/week) | 2069(18.49) | 640(26.90) | 643(26.03) | 666(27.28) | 697(28.91) | |
LMVPA (1–599 MET-mins/week) | 1375(12.29) | 303(10.06) | 347(11.00) | 348(11.74) | 377(13.89) | |
MMVPA (600–1199 MET-mins/week) | 1168(10.44) | 276( 9.15) | 286( 9.29) | 297(10.22) | 309(11.80) | |
HMVPA (≥ 1200 MET-mins/week) | 6580(58.79) | 1750(66.75) | 1669(64.57) | 1637(61.29) | 1524(54.44) | |
BMI | < 0.0001 | |||||
Normal | 3743(33.44) | 1091(38.31) | 975(34.59) | 842(28.22) | 835(29.35) | |
Overweight | 3504(31.31) | 905(33.29) | 916(34.82) | 898(32.78) | 785(29.16) | |
Obese | 3945(35.25) | 802(28.40) | 907(30.60) | 1062(39.00) | 1174(41.49) | |
WC | 96.88(0.32) | 93.87(0.47) | 95.38(0.47) | 98.52(0.47) | 99.31(0.44) | < 0.0001 |
Muscle Quality | < 0.001 | |||||
Extremely low | 1319(12.81) | 285(22.47) | 299(22.24) | 320(25.19) | 415(30.50) | |
Low | 1187(9.62) | 272(18.16) | 275(17.85) | 316(20.26) | 324(19.48) | |
Normal | 3246(28.22) | 831(59.37) | 872(59.91) | 783(54.55) | 760(50.02) | |
Insulin resistance | < 0.0001 | |||||
Yes | 5512(47.33) | 1172(39.83) | 1354(45.64) | 1457(50.54) | 1529(52.23) | |
No | 5680(52.67) | 1626(60.17) | 1444(54.36) | 1345(49.46) | 1265(47.77) | |
DM | 0.001 | |||||
Yes | 1059(9.46) | 231(6.43) | 247(6.30) | 268(7.90) | 313(9.02) | |
No | 10,133(90.54) | 2567(93.57) | 2551(93.70) | 2534(92.10) | 2481(90.98) | |
Hypertension | 0.001 | |||||
Yes | 2927(26.15) | 681(23.12) | 682(23.39) | 759(26.28) | 805(29.36) | |
No | 8265(73.85) | 2117(76.88) | 2116(76.61) | 2043(73.72) | 1989(70.64) | |
Hyperlipidemia | < 0.0001 | |||||
Yes | 6756(60.36) | 1540(55.81) | 1683(59.55) | 1750(63.47) | 1783(63.82) | |
No | 4436(39.64) | 1258(44.19) | 1115(40.45) | 1052(36.53) | 1011(36.18) | |
NAFLD | < 0.0001 | |||||
Yes | 3746(33.47) | 792(27.12) | 895(29.29) | 1034(33.89) | 1025(35.63) | |
No | 7446(66.53) | 2006(72.88) | 1903(70.71) | 1768(66.11) | 1769(64.37) | |
ALT [U/L] | 25.76(0.24) | 26.21(0.59) | 26.25(0.44) | 26.03(0.51) | 24.65(0.40) | 0.02 |
AST [U/L] | 25.05(0.19) | 25.97(0.47) | 25.15(0.40) | 24.74(0.34) | 24.48(0.46) | 0.20 |
Creatinine [mg/dl] | 0.86(0.00) | 0.87(0.01) | 0.86(0.01) | 0.85(0.01) | 0.84(0.01) | < 0.001 |
Uric acid [umol/L] | 316.31(1.25) | 316.95(2.58) | 317.07(1.96) | 317.96(2.26) | 313.38(1.74) | 0.21 |
Total percentage fat [%] | 32.70(0.15) | 30.20(0.24) | 31.80(0.23) | 33.58(0.23) | 34.83(0.21) | < 0.0001 |
Android percentage fat [%] | 34.71(0.18) | 32.11(0.26) | 33.82(0.26) | 35.80(0.26) | 36.72(0.25) | < 0.0001 |
Gynoid percentage fat [%] | 35.30(0.13) | 33.07(0.25) | 34.51(0.21) | 36.01(0.24) | 37.27(0.20) | < 0.0001 |
Total abdominal fat area [cm2] | 432.44(4.14) | 377.17(5.58) | 408.14(5.71) | 455.29(6.17) | 480.84(5.71) | < 0.0001 |
Subcutaneous fat area [cm2] | 331.31(3.26) | 287.88(4.52) | 312.77(4.45) | 348.42(5.11) | 369.64(4.45) | < 0.0001 |
Visceral adipose tissue area [cm2] | 101.13(1.14) | 89.29(1.52) | 95.37(1.54) | 106.87(1.68) | 111.20(1.89) | < 0.0001 |
V/S ratio | 0.34 (0.00) | 0.36(0.00) | 0.34(0.00) | 0.34(0.00) | 0.33(0.00) | < 0.001 |