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Table 2 Univariate and stepwise forward multivariate regression analysis for associations between clinical characteristics and serum Klotho concentrations (log-normalized values)

From: Gender-specific association between circulating serum Klotho and metabolic components in adults

 

Univariate

Multivariable*

Coefficients

Beta

t

p

Coefficients

Beta

t

p

Female gender

0.027

0.091

4.53

< 0.001

0.021

0.069

3.45

< 0.001

Age, /10 years

-0.012

-0.086

-4.27

< 0.001

-0.011

-0.079

-3.99

< 0.001

BMI category

-0.024

-0.066

-3.30

0.001

-0.025

-0.069

-3.46

< 0.001

Tobacco use

-0.015

-0.108

-5.38

< 0.001

-0.014

-0.100

-4.95

< 0.001

WC, /10 cm

-0.003

-0.036

-1.80

0.072

-

   

SBP, /10mmHg

-0.003

-0.033

-1.62

0.104

-

   

MAP, /10mmHg

-0.002

-0.015

-0.76

0.446

-

   

PP, /10mmHg

-0.003

-0.034

-1.67

0.095

-

   
  1. BMI, body mass index, and BMI category include four levels (< 18.5 kg/m2, 18.5–25 kg/m2, 25–29.9 kg/m2, and > 30 kg/m2); WC, waist circumference; SBP, systolic blood pressure; MAP, mean artery pressure; PP, pulse pressure; tobacco use includes four levels (none, quit, some days, and every day). *Stepwise forward regression model after adjusting for ethnicity