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Table 4 Gender-specific stepwise forward multivariate regression analysis for independent associations with Klotho*

From: Gender-specific association between circulating serum Klotho and metabolic components in adults

 

Coefficients

Beta

t

p

Men

    

 Uric acid (mg/dl) *

-0.126

-0.085

-2.725

0.007

 Estradiol (pg/ml) *

0.069

0.081

2.751

0.006

 HDL (mg/dl) *

-0.182

-0.171

-5.500

< 0.001

 SHBG (nmol/l) *

0.114

0.167

4.872

< 0.001

 Tobacco use

-0.012

-0.090

-3.062

0.002

 Age/10

-0.009

-0.070

-2.224

0.026

 Creatinine (mg/dl) *

-0.084

-0.064

-2.071

0.039

 CRP (mg/l) *

-0.017

-0.062

-2.068

0.039

Women

    

 Uric acid (mg/dl) *

-0.137

-0.102

-3.361

0.001

 Tobacco use

-0.013

-0.086

-3.084

0.002

 Creatinine (mg/dl) *

-0.117

-0.091

-3.005

0.003

 Triglycerides (mg/dl) *

-0.039

-0.063

-2.152

0.032

 Age/10 years

-0.010

-0.067

-2.330

0.020

 WBC*

-0.072

-0.061

-2.038

0.042

  1. HDL, fasting high-density lipoprotein cholesterol level; FPG, fasting plasma glucose; WBC, white blood cell. Tobacco use includes four levels (none, quit, some days, and every day). * Log-normalized values