Fig. 3

MR analysis using SNPs with locus-wide significance. (a) The results of MR analysis, heterogeneity test, pleiotropy test; (b) Sensitivity analysis of the MR analysis between phylum Bacteroidetes and DN; (c) Scatter plot of MR analysis for the family Verrucomicrobiaceae and DN; (d) Scatter plot of MR analysis for the phylum Bacteroidetes and DN; (e) Scatter plot of MR analysis for the genus Akkermansia and DN; (f) Scatter plot of MR analysis for the genus Coprococcus2 and DN; (g) Scatter plot of MR analysis for the genus Catenibacterium and DN; (h) Scatter plot of MR analysis for the genus Eubacterium_coprostanoligenes_group and DN