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Table 1 Result of corticotropin-releasing hormone stimulation test

From: Ectopic adrenocorticotrophic hormone syndrome in a 10-year-old girl with a thymic neuroendocrine tumor: a case report

Time (min)

-15

0

15

30

45

60

90

120

Serum cortisol

(normal range 68.2–537 nmol/l)

795

839

1021

1048

(↑32%)

958

895

863

875

Plasma ACTH

(normal range 1.6–13.9 pmol/l)

27.11

27.01

45.21

(↑67%)

36.94

33.37

30.39

29.06

29.79

  1. The highest increase of cortisol/ACTH and percentage increases are indicated in bold and in the brackets. An increase of 20% above baseline for cortisol values and an increase of at least 35% over basal values for ACTH concentration is suggestive of CD. A dose of 1 mcg/kg IV of corticotropin-releasing hormone was given. Normal range refers to laboratory reference values. Abbreviation: ACTH, adrenocorticotrophic hormone