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Table 2 Relationship between lipid parameters and diabetes

From: Lipids as the link between central obesity and diabetes: perspectives from mediation analysis

 

HR (95%CI)

Unadjusted Model

Model 1

Model 2

 

TC

1.41 (1.29, 1.55) **

1.15 (1.04, 1.28) *

0.95 (0.85, 1.06)

 

TG

1.47 (1.41, 1.54) **

1.26 (1.17, 1.34) **

1.14 (1.05, 1.23) *

 

HDL-C

0.44 (0.38, 0.50) **

0.66 (0.57, 0.77) **

0.74 (0.63, 0.86) **

 

LDL-C

1.63 (1.51, 1.77) **

1.25 (1.12, 1.39) **

1.00 (0.90, 1.12)

 

Non-HDL-C

1.70 (1.57, 1.84) **

1.28 (1.15, 1.42) **

1.02 (0.91, 1.14)

 

RC

1.84 (1.71, 1.98) **

1.38 (1.25, 1.52) **

1.11 (1.01, 1.23) *

 

TC/HDL-C ratio

1.81 (1.69, 1.94) **

1.37 (1.25, 1.51) **

1.18 (1.07, 1.31) *

 

TG/HDL-C ratio

1.33 (1.29, 1.37) **

1.22 (1.16, 1.29) **

1.15 (1.07, 1.22) **

 

LDL/HDL-C ratio

1.79 (1.67, 1.92) **

1.36 (1.24, 1.50) **

1.17 (1.06, 1.30) *

 

Non-HDL/HDL-C ratio

1.81 (1.69, 1.94) **

1.37 (1.25, 1.51) **

1.18 (1.07, 1.31) *

 

RC/HDL-C ratio

1.66 (1.58, 1.75) **

1.36 (1.25, 1.48) **

1.20 (1.09, 1.31) **

 
  1. Abbreviations: HDL-C: high-density lipoprotein cholesterol; TC: total cholesterol; TG: triglyceride; LDL-C: low density lipoprotein cholesterol; Non-HDL-C: non-high-density lipoprotein cholesterol; RC: remnant cholesterol
  2. Model 1 adjusted sex, age, height, fatty liver, habit of exercise, smoking status and drinking status
  3. Model 2 adjusted model 1 + SBP, FPG, HbA1c, ALT, AST and GGT
  4. *P < 0.05, **P < 0.001