Relationship of different metabolic obesity phenotypes with reflux esophagitis: a propensity score matching analysis

Table 5 Association of metabolic obesity phenotypes at baseline with risk of RE by sex

Variables	Cases	Model 1		Model 2		Model 3
Variables	Cases	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value
All
MHNW	1,739	1(Reference)		1(Reference)		1(Reference)
MHO	1,329	2.448(2.023–2.961)	< 0.001	3.575(2.846–4.490)	< 0.001	3.742(2.960–4.731)	< 0.001
MUNW	3,885	1.980(1.681–2.332)	< 0.001	1.986(1.685–2.340)	< 0.001	1.763(1.490–2.085)	< 0.001
MUO	2,994	3.387(2.875–3.989)	< 0.001	4.798(3.912–5.885)	< 0.001	4.590(3.720–5.665)	< 0.001
Male
MHNW	873	1(Reference)		1(Reference)		1(Reference)
MHO	644	2.540(1.945–3.318)	< 0.001	3.071 (2.227–4.234)	< 0.001	3.110(2.235–4.328)	< 0.001
MUNW	1,441	2.046(1.615–2.592)	< 0.001	2.046(1.614–2.594)	< 0.001	1.721(1.349–2.195)	< 0.001
MUO	1,261	3.525(2.792–4.450)	< 0.001	4.159(3.100–5.581)	< 0.001	3.723(2.751–5.040)	< 0.001
Female
MHNW	866	1(Reference)		1(Reference)		1(Reference)
MHO	685	2.365(1.802–3.104)	< 0.001	4.149(2.997–5.745)	< 0.001	4.330(3.096–6.055)	< 0.001
MUNW	2,444	1.968(1.564–2.475)	< 0.001	1.985(1.577–2.499)	< 0.001	1.803(1.424–2.283)	< 0.001
MUO	1,733	3.319(2.633–4.183)	< 0.001	5.559(4.172–7.406)	< 0.001	5.482(4.080–7.367)	< 0.001

MHNW, metabolically healthy normal weight; MHO, metabolically healthy obesity; MUNW, metabolically unhealthy normal weight; MUO, metabolically unhealthy obesity
Model 1: not adjusted
Model 2: adjusted for age, and BMI
Model 3: adjusted for age, BMI, smoking, alcohol, and H. pylori

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