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Table 1 Baseline characteristics of participants by cognition status

From: Association of time in range with cognitive impairment in middle-aged type 2 diabetic patients

Variables

All subjects

(n = 274)

CI

(n = 114)

NCF

(n = 160)

P value

Male

124 (45.3%)

53 (46.5%)

71 (44.4%)

0.729

Age (years)

58.0 (54.0,62.0)

58.0 (55.0,62.0)

57.0 (54.0,61.0)

0.092

 40–44(years)

8 (2.9%)

1 (0.9%)

7 (4.4%)

 

 45–59(years)

150 (54.7%)

58 (50.9%)

92 (57.5%)

 

 60–64(years)

116 (42.3%)

55 (48.2%)

61 (38.1%)

 

Education(years)

12.0 (9.0,12.0)

9.0 (9.0,12.0)

12.0 (9.0,12.0)

0.014

Age at DM onset (years)

52.0 (45.0,57.0)

53.0 (46.0,57.5)

50.5 (44.0,56.0)

0.238

Ethnic Han

244 (89.1%)

104 (91.2%)

140 (87.5%)

0.330

Married

251 (91.6%)

96 (84.2%)

155 (96.9%)

<0.001

Sedentary lifestyle

66 (24.2%)

25 (21.9%)

41 (25.8%)

0.463

Diabetic diet control

163 (59.7%)

64 (56.1%)

99 (62.3%)

0.309

Use antidiabetic agents

    

 Insulin

135 (49.3%)

60 (52.6%)

75 (46.9%)

0.347

 Insulin secretagogues

121 (44.2%)

51 (44.7%)

70 (43.8%)

0.871

Hypoglycemic events in last 3 months

59 (21.9% )

28 ( 25.0%)

31 (19.7%)

0.305

Diabetic microangiopathy

126 (46.2%)

56 (49.6%)

70 (43.8%)

0.103

CVD

54 (19.8%)

35 (31.0%)

19 (11.9%)

<0.001

Hypertension

173 (63.4%)

71 (62.8%)

102 (63.7%)

0.876

WBC(109/L)

5.9 (5.1, 7.2)

5.8 (5.1, 7.2)

5.9 (5.1, 7.1)

0.813

NLR

1.7 (1.3, 2.2)

1.6 (1.3, 2.1)

1.7 (1.4, 2.2)

0.412

RBC(1012/L)

4.5 (4.2, 4.8)

4.5 (4.1, 4.8)

4.5 (4.2, 4.8)

0.908

Hb(g/L)

135.9 ± 14.9

136.3 ± 15.1

135.7 ± 14.8

0.753

ALT(U/L)

20.9 (14.2, 34.2)

31.4 (18.1, 53.6)

34.3 (21.8, 52.9)

0.181

Cr(µmol/L)

55.0 (46.8, 63.0)

63.0 (56.0, 67.7)

64.0 (53.0, 73.7)

0.358

TC(mmol/L)

5.0 (4.3, 5.6)

5.6 (5.0, 6.4)

5.7 (5.0, 6.5)

0.600

TG(mmol/L)

1.7 (1.2, 2.48)

2.6 (1.6, 4.5)

2.5 (1.7, 4.5)

0.953

LDL-C(mmol/L)

2.8 (2.5, 3.4)

3.4 (2.9, 3.9)

3.43 (2.9, 4.0)

0.871

HDL-C(mmol/L)

1.2 (1.1, 1.4)

1.4 (1.2, 1.6)

1.4 (1.2, 1.6)

0.424

TSH(µIU/mL)

2.8 (1.9, 4.4)

2.8 (1.8, 4.5)

2.8 (2.0, 4.2)

0.839

  1. The measurement data are shown as mean ± standard deviation (SD) or median and interquartile range [P25, P75], depending on the normality of data distribution. Categorical data are presented as the number of cases (percentage) [n (%)]. P < 0.05 was regarded as a significant difference
  2. CI, cognitive impairment; NCF, normal cognitive function; CVD, cerebrovascular disease; WBC, white blood cell count; NLR, neutrophil count to lymphocyte ratio; RBC, red blood cell count; Hb, hemoglobin; ALT, alanine aminotransferase; Cr, serum creatinine; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TSH, thyroid stimulating hormone