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Table 4 Association between tertiles of TIR and cognitive impairment

From: Association of time in range with cognitive impairment in middle-aged type 2 diabetic patients

Tertiles of TIR

No.

unadjusted

 

Model 1

 

Model 2

 

Model 3

 

Model 4

  

OR (95%CI)

 

OR (95%CI)

 

OR (95%CI)

 

OR (95%CI)

 

OR (95%CI)

T1(≤ 17%)

107

1.00 (ref)

 

1.00(ref)

 

1.00(ref)

 

1.00(ref)

 

1.00(ref)

T2(17–50%)

86

0.64(0.36–1.14)

 

0.61(0.33–1.11)

 

0.59(0.32–1.10)

 

0.59(0.32–1.11)

 

0.52(0.27–1.01)

T3(> 50%)

81

0.46(0.25–0.85)*

 

0.34(0.18–0.66)#

 

0.32(0.16–0.62)#

 

0.33(0.17–0.67)#

 

0.29(0.14–0.58)#

P for trend

 

0.011

 

0.001

 

0.001

 

0.002

 

< 0.001

  1. aModel 1: adjusted for age, education, marital status; Model 2: Model 1 + age at DM onset and cerebrovascular disease (CVD). Model 3: Model 2 + SD. Model 4: Model 2 + CV
  2. b P values for linear trends were calculated using the median value of tertiles of TIR
  3. *p value<0.05,#p value<0.01
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BMC Endocrine Disorders

ISSN: 1472-6823

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