From: Thyroid hormone levels in patients with bipolar disorder: a systematic review and meta-analysis
 | Outcome indicators | Number of studies omitted | The pooled results after omitting unstable studies | ||||
---|---|---|---|---|---|---|---|
N | SMD | 95%CI | I2 (%) | P-value | |||
BD-D and HC | TSH | 3 | 8 | -0.16 | (-0.38 to 0.07) | 44.00 | 0.172 |
T4 | 3 | 5 | -0.06 | (-0.32 to 0.20) | 44.40 | 0.649 | |
FT3 | 3 | 6 | -0.77 | (-1.12 to -0.42) | 83.90 | 0.000 | |
BD-M and HC | T3 | 2 | 5 | -0.91 | (-1.49 to -0.32) | 86.20 | 0.002 |
FT4 | 1 | 5 | 0.37 | (0.14 to 0.60) | 40.00 | 0.002 | |
BD-M and BD-D | T4 | 2 | 6 | 0.16 | (-0.12 to 0.43) | 77.60 | 0.267 |