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Table 1 Characteristics of the included studies

From: Impact of gestational diabetes mellitus on women’s sexual function: a systematic review and meta-analysis

First author/date of publication/country

Type of studies

Sample size

Age of participants (years)

Gestational age (weeks)

Race

BMI (kg/m2)

Comparison

Outcome measurements

Outcome

Results

NOS

Souza et al. [23]/Brazil

Cross-Sectional

GDM group: 33

Control group: 55

GDM group: 30.94 ± 6.2

Control group: 26.1 ± 6.0

20

to 25 weeks

GDM group: White = 32%

Nonwhite = 68%

Control group: White = 45% Nonwhite = 55%

NR

Low-risk pregnancy

FSFI

Total score of Sexual Function

Prevalence of sexual dysfunction

Sexual function domains (sexual desire, arousal, lubrication, orgasm,

satisfaction, and pain)

There was no statistically significant difference in the total score of sexual function, orgasm, and satisfaction scores between the groups with GDM and the control groups.

7

Ribeiro et al. [24]/Brazil

Cross-Sectional

GDM group: 44

Control group: 43

GDM group: 30.8 ± 5.2

Control group: 29.2 ± 5.5

GDM group: 33.8 ± 3.0

Control group: 33.9 ± 3.6

GDM group: White = 54.5%

Nonwhite = 45.5%

Control group: White = 53.5%

Nonwhite = 46.5%

NR

Healthy

Pregnancy

FSFI

Total score of Sexual Function

Sexual function domains (sexual desire, arousal, lubrication, orgasm,

satisfaction, and pain)

There was no statistically significant difference observed in the total score of sexual function (P = 0.523), sexual desire (P = 0.775), arousal (P = 0.407), lubrication (P = 0.749), orgasm (P = 0.655), satisfaction (P = 0.956), and pain (P = 0.571) scores between the groups diagnosed with GDM and the control groups.

7

Nunes et al. [26]/ Brazil

CCase-Control

GDM group: 108

Control group: 168

GDM group: 28.9 ± 4.7

Control group: 25.1 ± 5.3

GDM group: 37.0 ± 2.7

Control group: 35.4 ± 3.2

NR

GDM group: 33.25 ± 5.44

Control group: 30.22 ± 5.45

Healthy

Pregnancy

PSRI

Total score of Sexual Function

Prevalence of sexual dysfunction

Sexual function domains (sexual desire, arousal, orgasm,

satisfaction, pain, and frequency of sexual relations)

There was a statistically significant difference in the prevalence of sexual dysfunction (P < 0.0001), total score of sexual function (P < 0.0001), frequency, arousal, orgasm, satisfaction, pain, and female difficulties score (P < 0.0001) between the groups diagnosed with GDM and the control groups.

6

Zare et al. [27]/Iran

Cross-Sectional

GDM group: 150

Control group: 150

GDM group: 31.31 ± 0.46

Control group: 28.73 ± 0.41

GDM group: 34.38 ± 0.18

Control group: 34.78 ± 0.2

GDM and control groups = White 100% (Persian)

NR

low-risk pregnancy

FSFI

Total score of Sexual Function

Sexual function domains (sexual desire, arousal, lubrication, orgasm,

satisfaction, and pain)

There was a statistically significant difference in the total score of sexual function (P = 0.001), sexual desire (P = 0.001), lubrication (P = 0.003), satisfaction (P = 0.001), and pain (P = 0.004) scores between the groups diagnosed with GDM and the control groups.

9

Ozcan et al. [28]/Turkey

Cross-Sectional

GDM group: 65

Control group: 65

GDM group: 31.68 ± 3.23

Control group: 29.48 ± 4.06

GDM group: 32.14 ± 3.96

Control group: 31.35 ± 6.08

GDM and control groups = White 100% (Turkish)

NR

Healthy

Pregnancy

GRISS

Total score of sexual function

Sexual function domains (Satisfaction and frequency of sexual relations)

There was a statistically significant difference in the total score of sexual function (P < 0.0001) and sexual satisfaction (P < 0.0001) between the groups diagnosed with GDM and the control groups.

7

Tabande et al. [25]/Iran

Cross-Sectional

GDM group: 75

Control group: 75

27.8 ± 5.7

NR

GDM and control groups = White 100% (Persian)

NR

Healthy

Pregnancy

FSFI

Total score of Sexual Function

Sexual function domains (sexual desire, arousal, lubrication, orgasm,

satisfaction, and pain)

There was no statistically significant difference in the total score and domain-specific scores of sexual function between the groups diagnosed with GDM and the control groups.

5

  1. FSFI = Female Sexual Function Index, PSRI = Pregnancy Sexual Response Inventory, GRISS = Golombok-Rust Inventory of Sexual Satisfaction Female Questionnaire, GDM = Gestational Diabetes Mellitus, BMI = Body Mass Index, NR = Not Reported