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Table 2 Summary of findings for the main comparison. Sexual function in women diagnosed with gestational diabetes. Patient or population: GDM women. Setting: Brazil; Iran; and Turkey. Exposure: GDM. Comparison: Non-GDM women

From: Impact of gestational diabetes mellitus on women’s sexual function: a systematic review and meta-analysis

Outcomes

Anticipated absolute effects [95% CI]

Relative effect [95% CI]

No of

Participants

[studies]

Quality of

the evidence

Risk with non-GDM

Risk with GDM

Total score of sexual function

The mean of the total score of sexual function

in the control groups was

46.16

The mean of the total score of sexual function

in the GDM group

was 1.80 [-3.44, -0.15]

SMD − 1.80 [-3.44, -0.15]

881 [4 Cross-Sectional and 1 Case–Control]

Low a

OO

Sexual desire

The mean of sexual desire

in the control groups was

34.96

The mean of sexual desire

in the GDM group

was − 5.31 [-8.31, -2.30]

SMD − 5.31 [-8.31, -2.30]

751 [3 Cross-Sectional and 1 Case–Control]

Low a, b

OO

Arousal

The mean of arousal

in the control groups was

29.39

The mean of arousal in the GDM group

was − 0.56 [-0.92, -0.21]

SMD − 0.56 [-0.92, -0.21]

751 [3 Cross-Sectional and 1 Case–Control]

Low c, b

OO

Lubrication

The mean of lubrication

in the control groups was

26.23

The mean of lubrication in the GDM group

Was − 2.51 [-7.36, 2.33]

MD -2.51 [-7.36, 2.33]

475 [3 Cross-Sectional]

Low a, b

OO

Orgasm

The mean of orgasm

in the control groups was

27.86

The mean of orgasm in the GDM group

Was − 1.21 [-2.80, 0.38]

SMD − 1.21 [-2.80, 0.38]

751 [3 Cross-Sectional and 1 Case–Control]

Low a, b

OO

Satisfaction

The mean of satisfaction

in the control groups was

29.27

The mean of satisfaction in the GDM group

Was − 4.29 [-6.59, -2.00]

SMD − 4.29 [-6.59, -2.00]

881 [4 Cross-Sectional and 1 Case–Control]

Low a, b

OO

Pain

The mean of pain

in the control groups was

38.40

The mean of pain in the GDM group

Was 0.83 [-1.25, 2.91]

SMD 0.83 [-1.25, 2.91]

751 [3 Cross-Sectional and 1 Case–Control]

Low a, b

OO

  1. Low quality: the actual effect may vary significantly from the estimated value
  2. a The statistical tests indicate high heterogeneity (I2 = 99%, p < 0.001) despite relatively good overlap of confidence intervals, leading to a 2-level downgrade in the assessment
  3. b The evidence was rated down by 1 level due to imprecision caused by a wide confidence interval
  4. c The statistical tests revealed high heterogeneity (I2 = 80%, p < 0.001) despite the relatively good overlap in the confidence intervals. This led to a 1-level downgrade in the assessment