Table 3 Univariable and multivariable analyses using the Cox-proportional hazard model for predictor's of macrovascular complications among T2DM patients in JMC, Oromia Region, Southwest Ethiopia from January 1, 2018 to December 31, 2022 G.C

Gender

Female

91

110

1.27(0.95,1.70)

0.113

0.80(0.58,1.11)

0.188

Male

86

147

1

Age-category in years

≥ 60 years

123

40

13.81(5.62,33.93)

0.000

4.42(1.72,11.29)

0.002

40–59 years

49

172

3.42(1.20,7.61)

0.018

2.28(0.89,5.82)

0.083

18–39 years

5

45

1

Residence

Urban

143

99

3.63(2.49,5.27)

0.000

2.02(1.34,3.05)

0.001

Rural

34

158

1

Hypertension

Yes

118

74

2.66(1.94,3.63)

0.000

1.50(1.06,2.14)

0.020

No

59

183

1

Dyslipidemia

Yes

23

4

3.11(2.07,4.68)

0.000

1.82(1.13,2.93)

0.014

No

154

253

1

BMI

Obese

48

9

2.99(0.72,12.38)

0.129

1.31(0.28,6.08)

0.733

Overweight

54

19

2.99(0.72,12.38)

0.129

1.33(0.28,6.08)

0.733

Normal weight

73

226

0.94(0.23,3.85)

0.935

1.40(1.13,2.93)

0.659

Underweight

2

3

1

Cholesterol

> 200 mg/dl

133

50

4.73(3.36,6.67)

0.000

1.38(0.75,2.53)

0.300

≤ 200 mg/dl

44

207

1

HDL-C

< 40 mg/dl

135

46

5.31(3.74,7.55)

0.000

2.11(1.16,3.81)

0.013

≥ 40 mg/dl

42

211

1

LDL-C

> 100 mg/dl

113

55

3.14(2.30,4.27)

0.000

0.73(0.48,1.11)

0.144

≤ 100 mg/dl

64

202

1

Triglyceride

> 150 mg/dl

113

81

2.43(1.78,3.31)

0.000

1.48(1.02,2.13)

0.037

≤ 150 mg/dl

64

176

1

Protein urea

Positive

62

19

2.76(2.02,3.77)

0.000

1.06(0.74,1.51)

0.737

Negative

115

238

1

HgbA1C

7%

123

77

2.84(2.06,3.92)

0.000

1.49(1.04,2.14)

0.029

≤ 7%

54

180

1

Family history of CVD

Yes

42

2

3.18(2.24,4.52)

0.000

1.25(0.84,1.88)

0.268

No

135

255

1

Medications

Both

69

20

5.39(3.79,7.66)

0.000

2.73(1.81,4.09)

0.0001

Injections

45

36

2.47(1.68,3.63)

0.000

1.49(0.97,2.27)

0.062

OHA

63

201

1