Table 1 Baseline characteristics of the subjects
Characteristics | All Participants (n = 423) | Low-level SII (≤ 381.32) (n = 141) | Moderate-level SII (381.32–629.46) (n = 141) | High-level SII (≥ 629.46) (n = 141) | P values |
|---|---|---|---|---|---|
Age, years | 69.00 (64.00,75.00) | 67.00 (62.00,74.00) | 70.00 (64.00,76.00) | 72.00 (65.00,76.00) | 0.012* |
Osteoporosis, n (%) | Â | Â | Â | Â | 0.740 |
 No | 129 (30.5) | 46 (32.6) | 43 (30.5) | 40 (28.4) |  |
 Yes | 294 (69.5) | 95 (67.4) | 98 (69.5) | 101 (71.6) |  |
Hypertension, n (%) |  |  |  |  |  < 0.001* |
 No | 146 (34.5) | 68 (48.2) | 45 (31.9) | 33 (23.4) |  |
 Yes | 277 (65.5) | 73 (51.8) | 96 (68.1) | 108 (76.6) |  |
DPN, n (%) | Â | Â | Â | Â | 0.777 |
 No | 158 (37.4) | 56 (39.7) | 51 (36.2) | 51 (36.2) |  |
 Yes | 265 (62.6) | 85 (60.3) | 90 (63.8) | 90 (63.8) |  |
PVD, n (%) | Â | Â | Â | Â | 0.973 |
 No | 41 (9.7) | 13 (9.2) | 14 (9.9) | 14 (9.9) |  |
 Yes | 382 (90.3) | 128 (90.8) | 127 (90.1) | 127 (90.1) |  |
Fracture history, n (%) | Â | Â | Â | Â | 0.965 |
 No | 503 (77.9) | 104 (73.8) | 10 2(72.3) | 103 (73.0) |  |
 Yes | 143 (22.1) | 37 (26.2) | 39 (27.7) | 38 (27.0) |  |
Duration of diabetes, years | 10.00 (3.00,16.00) | 8.00 (2.00,16.00) | 10.00 (3.00,16.50) | 9.00 (3.00,15.00) | 0.284 |
BMI, kg/m2 | 24.24 (22.07,26.78) | 24.22 (22.35,26.91) | 24.61 (22.50,26.81) | 23.83 (21.48,26.51) | 0.252 |
FBG, mmol/L | 7.27 (5.64,9.62) | 6.80 (5.44,9.19) | 7.59 (5.76,9.73) | 7.28 (5.66,10.38) | 0.315 |
HbA1c, % | 8.20 (6.90,10.40) | 8.00 (6.60,10.60) | 8.40 (7.05,10.50) | 8.50 (6.80,10.25) | 0.541 |
Hb, g/L | 125.00 (115.00,134.00) | 126.00 (117.00,134.00) | 126.00 (118.50,135.00) | 122.00 (105.50,133.00) |  < 0.001* |
TSH, μIU/mL | 1.68 (1.08,2.61) | 1.72 (1.14,2.60) | 1.68 (1.16,2.61) | 1.62 (1.03,2.68) | 0.902 |
FT3, pmol/L | 4.50 (4.09,4.92) | 4.52 (4.12,4.95) | 4.56 (4.10,5.01) | 4.37 (4.04,4.77) | 0.066 |
FT4, pmol/L | 11.25 (9.83,13.20) | 10.88 (9.98,12.70) | 11.26 (9.70,13.07) | 11.69 (9.65,13.83) | 0.293 |
TC, mmol/L | 4.89 (4.00,5.75) | 4.90 (4.04,5.77) | 4.84 (4.00,5.70) | 4.90 (3.89,5.78) | 0.973 |
TG, mmol/L | 1.42 (1.04,2.05) | 1.42 (1.06,1.99) | 1.46 (1.07,2.09) | 1.38 (0.98,2.10) | 0.814 |
HDL-C, mmol/L | 1.17 (1.01,1.38) | 1.16 (0.99,1.35) | 1.21 (1.03,1.42) | 1.14 (0.99,1.36) | 0.191 |
LDL-C, mmol/L | 2.92 (2.27,3.61) | 2.94 (2.30,3.62) | 2.92 (2.27,3.59) | 2.88 (2.28,3.58) | 0.982 |
Cr, μmol/L | 65.00 (55.00,80.00) | 63.00 (53.50,72.50) | 64.00 (55.00,78.50) | 68.00 (54.50,94.50) | 0.034* |
UA, μmol/L | 317.00 (267.00,390.00) | 316.00 (266.50,394.50) | 321.00 (263.00,376.00) | 317.00 (272.00,392.00) | 0.976 |
Ca, mmol/L | 2.27 (2.20,2.36) | 2.28 (2.20,2.36) | 2.29 (2.23,2.37) | 2.26 (2.17,2.35) | 0.034* |
25(OH) D, nmol/L | 54.42 ± 22.54 | 58.75 ± 22.97 | 55.44 ± 23.16 | 49.06 ± 20.46 | 0.001* |
ALB, g/L | 38.40 (35.30,41.00) | 38.90 (36.70,41.55) | 39.00 (36.15,41.00) | 36.40 (32.40,40.00) |  < 0.001* |
SII | 481.72 (337.92–721.26) | 274.29 (226.13–337.90) | 481.72 (424.43–526.97) | 904.25 (722.28–1294.11) |  < 0.001* |
LS BMD, g/cm2 | 0.744 (0.657,0.841) | 0.733 (0.655,0.832) | 0.770 (0.674,0.859) | 0.732 (0.649,0.824) | 0.138 |
FN BMD, g/cm2 | 0.556 (0.494,0.631) | 0.586 (0.510,0.655) | 0.555 (0.504,0.625) | 0.539 (0.458,0.613) | 0.011* |
TH BMD, g/cm2 | 0.704 ± 0.130 | 0.722 ± 0.127 | 0.711 ± 0.129 | 0.679 ± 0.132 | 0.016* |
FRAX MOF, % | 6.10 (4.10,9.60) | 5.60 (3.65,8.55) | 6.20 (4.40,9.45) | 7.20 (4.20,12.00) | 0.025* |
FRAX HF, % | 2.30 (1.10,4.40) | 1.90 (0.80,3.65) | 2.40 (1.30,4.10) | 2.80 (1.20,6.10) | 0.009* |