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Table 3 Metabolic profiles at baseline and after eight-week intervention in patients with PCOS

From: Modulation of hormonal, metabolic, inflammatory and oxidative stress biomarkers in women with polycystic ovary syndrome following combined (resistant and endurance) training: a randomized controlled trail

Variables

Control group

Combined training group

Pvalueb

Æž

Baseline

Week 8

Change

Pvaluea

Baseline

Week 8

Change

Pvaluea

  

FPG (mg/dl)

98.53±4.44

98.86±4.71

0.33±1.56

0.25

97.86±4.12

97.30±4.08

0.56±2.04

0.57

0.31

0.03

Insulin (µU/ml)

11.03±1.65

11.08±1.61

0.05±0.49

0.38

11.23±1.56

10.48±1.46

−0.75±0.28

0.001

0.001

0.35

HOMA-IR

2.69+0.49

2.72±0.49

0.02±0.13

0.24

2.72±0.47

2.52±0.42

−0.19±0.08

0.001

0.001

0.35

QUICKI

0.33±0.009

0.32±0.009

−0.0003±0.004

0.25

0.32±0.008

0.33±0.008

0.002±0.004

0.006

0.002

0.29

Total-Chol (mg/dl)

170.73±12.76

171.03±12.65

0.30±1.44

0.19

171.66±13.27

162.13±13.43

−9.53±1.54

0.001

0.001

0.43

Triglyceride (mg/dl)

147.33±13.56

147.83±12.67

0.50±3.01

0.66

148.73±10.42

147.76±10.84

−0.96±4.42

0.18

0.39

0.02

LDL-C (mg/dl)

103.70±7.18

104.16±7.79

0.46±2.03

0.39

105.08±7.96

95.51±8.41

−9.57±2.23

0.001

0.001

0.68

HDL-C (mg/dl)

37.56±3.97

37.30±3.85

−0.26±1.48

0.11

36.83±5.81

37.06±5.81

0.23±1.07

0.76

0.48

0.01

AMH (ng/ml)

4.45±1.31

4.50±1.34

0.05±0.30

0.69

4.24±1.28

4.19±1.27

−0.05±0.18

0.23

0.02

0.16

Testosterone (ng/ml)

1.04±0.24

1.06±0.24

0.01±0.10

0.27

1.10±0.24

1.04±0.22

−0.06±0.05

0.001

0.001

0.47

FAI

2.14±0.45

2.18±0.46

0.04±0.24

0.29

2.21±0.25

2.07±0.23

−0.14±0.13

0.001

0.001

0.40

SHBG (nmol/l)

49.20±7.75

48.73±7.43

−0.46±1.71

0.24

49.40±7.01

50.04±7.74

0.64±2.25

0.34

0.16

0.06

MDA (µmol/l)

2.23±0.24

2.24±0.24

0.006±0.05

0.52

2.22±0.26

2.21±0.25

−0.009±0.04

0.57

0.04

0.14

TAC (mmol/l)

1.17±0.24

1.16±0.25

−0.01±0.03

0.86

1.13±0.21

1.14±0.21

0.01±0.06

0.07

0.37

0.02

hs-CRP (mg/l)

2.37±0.43

2.40±0.44

0.02±0.09

0.36

2.52±0.72

2.49±0.68

−0.03±0.13

0.42

0.24

0.04

  1. P values calculated using two-way analysis of variance followed with BonferroniÌ› s post-hoc test
  2. FPG Fasting plasma glucose, HOMA-IR Homeostasis model of assessment-insulin resistance, QUICKI Quantitative insulin sensitivity check index, LDL-C Low-density lipoprotein-cholesterol, HDL-C High-density lipoprotein-cholesterol, AMH Anti-Müllerian Hormone, FAI Free androgen index, SHBG Sex hormone binding globulin, MDA Malondialdehyde, TAC Total antioxidant capacity, hs-CRP high sensitive-C reactive protein
  3. È  Effect size of training protocol
  4. *Obtained from ANOVA test. All values are means ± SD
  5. aSignificant difference with pre-test (p < 0.05)
  6. bSignificant difference with the changes of the control group (∆) (p < 0.05)