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Table 1 Participant characteristics

From: The potential of insulin resistance indices to predict non-alcoholic fatty liver disease in patients with type 2 diabetes

Variables

NAFLD Group (T2DM with NAFLD) (n = 145)

T2DMGroup(T2DM without NAFLD) (n = 123)

P value

Demographic parameters

Age(years)

49.0(40.0,60.0)

56.0(47.0,61.0)

< 0.001

Sex (%)

 Female

52(35.9)

52(42.2)

0.315

 Male

93(64.1)

71(57.8)

DM duration (years)

4(2,5)

4(3,6)

0.057

Cigarette smoking (%)

77(53.1)

56(45.5)

0.217

 SBP

130(119.5,149

133(118,148)

0.730

 DBP

80(71,93.5)

80(72,95)

0.654

Anthropometric parameters

 WC (cm)

97.40(88.7,106.0)

89.70(83.0,95.4)

< 0.001

 WHR (cm)

0.96(0.91,1.00)

0.91(0.87,0.95)

< 0.001

 BMI

28.50(25.70,31.07)

26.0(23.60,27.90)

< 0.001

Serum test

 ALT(U/L)

28.00(18.5,49.50)

20.00(14.00,27.00)

< 0.001

 GGT(U/L)

45.00(27.25,69.75)

25.00 (17.75,33.25)

< 0.001

 FBG (mmol/L)

7.09(5.47,9.41)

6.82(5.80,7.68)

0.015

 TC (mmol/L)

4.62(3.93,5.35)

4.40(3.63,5.02)

0.029

 TG (mmol/L)

2.03(1.52,1.85)

0.96(0.96,2.09)

< 0.001

 HDL-C(mmol/L)

1.18(1.00,1.35)

1.30(1.08,1.54)

< 0.001

 LDL-C(mmol/L)

2.79(2.31,3.36)

2.53(2.04,2.98)

0.003

 FINS (pmol/L)

8.50(7.40,10.20)

9.87(5.55,16.06)

0.276

 HbA1c (%)

12.11(7.3,16.95)

7.70(6.70,8.80)

< 0.001

Noninvasive indices

 TyG

2.05(1.46,2.41)

1.56(1.04,2.03)

0.001

 TyG-BMI

56.98(43.92,74.61)

38.41(26.43,56.39)

< 0.001

 TyG-WC

195.67(142.16,249.08)

136.35(88.54,186.62)

< 0.001

 TyG-WHR

1.89(1.45,2.44)

1.43(0.93,1.87)

< 0.001

 HOMA-IR

3.86(2.27,5.91)

2.71(1.46,5.27)

0.006

VCTE parameters

 CAP (dB/m)

313.00(286.0,336.0)

242(224.0,253.25)

< 0.001

vLSM (kPa)

7.0(5.3,9.82)

4.90(4.0,6.0)

< 0.001

  1. Abbreviations: WC Waist circumference, WHR Waist-to-Hip Ratio, BMI Body mass index, ALT Alanine aminotransferase, GGT γ-glutamyltransferase, FBG Fasting blood glucose, TC Cholesterol, TG Triglycerides, HDL High-density lipoprotein, LDL Low-density lipoprotein, HbA1c, Glycosylated hemoglobin, FINS Fasting insulin, TyG Triglyceride glucose, TyG-BMI Triglyceride glucose-body mass index, TyG-WC Triglyceride Glucose-Waist Circumference, HOMA-IR Homeostasis model assessment of insulin resistance index, CAP Controlled attenuation parameter, LSM Liver Stiffness Measurement