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Table 6 Response to GLP-1 M based on the combination of sex, age and NSAIDs

From: Predicting responsiveness to GLP-1 pathway drugs using real-world data

Age

Sex

NSAID usage

Number of subjects

Decrease in HbA1c

(mean ± SD)

Bonferroni-Adjusted p-Value

Age < = 40

Male

No

183

0.78 ± 2.17

5.12E-1

Yes

73

0.56 ± 2.42

Female

No

301

0.28 ± 1.70

8E00-3

Yes

119

0.82 ± 1.72

Age > 40

Male

No

1639

0.58 ± 1.66

2.42E-1

Yes

2050

0.50 ± 1.54

Female

No

1767

0.52 ± 1.43

2.00E-3

Yes

1724

0.36 ± 1.45

  1. Comparison of features of GLP-1M responders versus non-responders. Significant values are shown in bold in the right hand column