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Table 3 Differential diagnoses for hypokalemic hypertension

From: Unravelling a mystery of hypokalemic hypertension- a rare case report of a reninoma

Low renin and high aldosterone- primary aldosteronism

High renin and high aldosterone- secondary aldosteronism

Low renin and low aldosterone- Apparent aldosterone excess

I. Aldosterone-producing adenoma

I. Renovascular hypertension

I. Cushing syndrome

II. Bilateral adrenal forms of primary aldosteronism

II. Reninoma

II. Apparent mineralocorticoid excess syndrome

III. Familial forms of primary aldosteronism (including glucocorticoid-remediable hypertension)

III. Obstructive sleep apnoea

III. Liddle syndrome

  

IV. Excess consumption of grapefruit or liquorice

  

V. Congenital adrenal hyperplasia17α-hydroxylase and 11β-hydroxylase deficiencies