Table 3 Estimated mean differences from linear random effects model for HbA1c(%) levels

Age

 Age [1st degree]

−1.51(−1.74–−1.29)

< 0.001

−1.28(−1.51–−1.04)

< 0.001

−0.41(−0.54–−0.28)

< 0.001

 Age [2nd degree]

−2.03(−2.17–−1.88)

< 0.001

−1.73(−1.87–−1.58)

< 0.001

−0.57(−0.67–−0.46)

< 0.001

 Age [3rd degree]

−4.65(−5.14–−4.16)

< 0.001

−4.17(−4.69–−3.66)

< 0.001

−0.96(−1.27–−0.65)

< 0.001

 Age [4th degree]

−2.67(−2.81–−2.54)

< 0.001

−2.32(−2.45–−2.18)

< 0.001

−0.77(−0.90–−0.64)

< 0.001

Sex

 Female

Ref

Ref

Ref

Ref

Ref

Ref

 Male

−0.13(−0.16–−0.11)

< 0.001

−0.14(−0.17–−0.12)

< 0.001

0.06(0.03 – 0.08)

< 0.001

Year since index test

 Year 1

Ref

Ref

Ref

Ref

Ref

Ref

 Year 2

−0.16(−0.17–−0.15)

< 0.001

−0.24(−0.25–−0.22)

< 0.001

0.42(0.40 – 0.45)

< 0.001

 Year 3

−0.08(−0.10–−0.07)

< 0.001

−0.18(−0.19–−0.16)

< 0.001

0.58(0.55 – 0.61)

< 0.001

 Year 4

0.06(0.05 – 0.08)

< 0.001

−0.04(−0.06–−0.02)

< 0.001

0.8(0.76 – 0.83)

< 0.001

 Year 5

0.09(0.03 – 0.16)

0.006

−0.04(−0.12– 0.03)

0.267

1.02(0.88 – 1.15)

< 0.001

Monitoring adherence rate

 Low

Ref

Ref

Ref

Ref

Ref

Ref

 Moderate

−0.34(−0.37–−0.31)

< 0.001

−0.19(−0.23-−0.16)

< 0.001

−0.13(−0.17-−0.10)

< 0.001

 High

−0.92(−0.97-−0.87)

< 0.001

−0.5(−0.56-−0.44)

< 0.001

−0.28(−0.33–−0.24)

< 0.001