Table 1 Descriptive characteristics of participants in case and control groups & analytical results between case and each control group
Variable | Category | Case | Control (total) | P-value Case & total control | Control (relative) | P-value Case & relative control | Control (non-relative) | P-value Case & non-relative control |
|---|---|---|---|---|---|---|---|---|
Age, Year | 37.34 ± 7.6 | 40.41 ± 9.6 | 0.010 | 42.75 ± 11.4 | 0.001 | 37.93 ± 6.4 | 0.611 | |
Age of menarche, Year | 13.48 ± 1.6 | 13.67 ± 1.3 | 0.341 | 13.62 ± 1.3 | 0.558 | 13.72 ± 1.3 | 0.310 | |
BMI, Kg/M2 | 26.85 ± 4.5 | 25.77 ± 3.4 | 0.068 | 25.85 ± 3.8 | 0.141 | 25.69 ± 3.0 | 0.065 | |
Education, N(%) | Under Diploma | 13 (16.9) | 26 (17.6) | 0.127 | 23 (30.3) | 0.116 | 3 (4.2) | 0.001 |
Diploma | 18 (23.4) | 17 (11.5) | 11 (14.5) | 6 (8.3) | ||||
BSc/BA | 30 (39.0) | 65 (43.9) | 32 (42.1) | 33 (45.8) | ||||
MSc/MA & above | 16 (20.8) | 40 (27.0) | 10 (13.2) | 30 (41.7) | ||||
Job | House keeper | 39 (50.6) | 60 (40.5) | 0.012 | 50 (65.8) | 0.110 | 10 (13.9) | < 0.001 |
Self employed | 16 (20.8) | 17 (11.5) | 8 (10.5) | 9 (12.5) | ||||
Employee | 22 (28.6) | 71 (48.0) | 18 (23.7) | 53 (73.6) | ||||
Marriage | Married | 70 (90.9) | 139 (93.9) | 0.405 | 74 (97.4) | 0.090 | 65 (90.3) | 0.895 |
Blood group | A | 21 (27.3) | 37 (25) | 0.073 | 20 (26.3) | 0.541 | 17 (23.6) | 0.012 |
B | 13 (16.9) | 46 (31.1) | 20 (26.3) | 26 (36.1) | ||||
AB | 10 (13) | 22 (14.9) | 9 (11.8) | 13 (18.1) | ||||
O | 33 (42.9) | 43 (29.1) | 27 (35.5) | 16 (22.2) | ||||
Irregular menstruation | Yes | 28 (36.4) | 30 (20.3) | 0.009 | 12 (15.8) | 0.004 | 18 (25) | 0.133 |
Menopause | Yes | 12 (15.6) | 18 (12.2) | 0.474 | 14 (18.4) | 0.640 | 4 (5.6) | 0.048 |
OCP consumption | Yes | 21 (27.3) | 11 (7.4) | < 0.001 | 7 (9.2) | 0.004 | 4 (5.6) | < 0.001 |
Pregnancy history | Yes | 63 (81.8) | 128 (86.5) | 0.354 | 72 (94.7) | 0.013 | 56 (77.8) | 0.539 |
Abortion | Yes | 17 (22.1) | 19 (12.8) | 0.073 | 10 (13.2) | 0.148 | 9 (12.5) | 0.124 |
Live birth history | Yes | 60 (77.9) | 118 (79.7) | 0.752 | 68 (89.5) | 0.053 | 50 (69.4) | 0.239 |
Thyroid nodule | Yes | 33 (42.9) | 27 (18.2) | < 0.001 | 15 (19.7) | 0.002 | 12 (16.7) | 0.001 |
Goiter history | Yes | 9 (11.7) | 18 (12.2) | 0.917 | 14 (18.4) | 0.244 | 4 (5.6) | 0.185 |
Hyperthyroidism | Yes | 8 (10.4) | 17 (11.5) | 0.804 | 5 (6.6) | 0.398 | 12 (16.7) | 0.261 |
Hypothyroidism | Yes | 30 (39.7) | 42 (28.4) | 0.106 | 22 (28.9) | 0.191 | 20 (27.8) | 0.149 |
Other disease history | Yes | 14 (18.2) | 33 (22.3) | 0.471 | 21 (27.6) | 0.164 | 12 (16.7) | 0.808 |
Head & neck radiation | Yes | 34 (44.2) | 28 (18.9) | < 0.001 | 12 (15.8) | < 0.001 | 16 (22.2) | 0.005 |
Family cancer history | Yes | 37 (48.1) | ‒ | ‒ | ‒ | ‒ | 10 (13.9) | < 0.001 |