Triglyceride glucose-waist circumference as a useful predictor for diabetes mellitus: a secondary retrospective analysis utilizing a Japanese cohort study

Table 6 Impact of TyG-WC on diabetes in Prespecified and exploratory subgroups

Characteristic	No of patients	Effect size(95%CI)	P value	P for interaction
Age(years)				0.8054
<60	14,701	1.004 (1.002, 1.006)	0.0001
≥ 60	712	1.005 (0.998, 1.013)	0.1725
Gender				0.2293
Women	7026	1.006 (1.002, 1.009)	0.0036
Men	8387	1.003 (1.001, 1.005)	0.0082
Ethanol consumption (g/week)				0.2348
0	4717	1.005 (1.002, 1.007)	0.0003
> 0	10,696	1.003 (1.001, 1.006)	0.0012
Smoking status				0.4882
Never-smoker	9007	1.004 (1.001, 1.008)	0.0116
Ex-smoker	2947	1.005 (1.000, 1.009)	0.0527
Current-smoker	3459	1.002 (0.999, 1.005)	0.2007
Regular exerciser				0.5797
No	12,708	1.004 (1.001, 1.006)	0.0011
Yes	2705	1.005 (1.000, 1.009)	0.0351
SBP (mmHg)				0.6649
<140	14,648	1.004 (1.002, 1.006)	0.0006
≥ 140	765	1.002 (0.997, 1.008)	0.4237
DBP (mmHg)				0.6398
<90	14,666	1.004 (1.002, 1.006)	0.0007
≥ 90	747	1.002 (0.995, 1.009)	0.5427
BMI (kg/m²)				0.5635
<25	12,939	1.003 (1.001, 1.005)	0.0029
≥ 25	2474	1.004 (1.002, 1.006)	0.0009
Fatty liver				0.1077
No	12,718	0.002 (1.000, 1.005)	0.0642
Yes	2695	1.004 (1.002, 1.007)	0.0001
ALT				0.0431
Low	7580	0.999 (0.995, 1.004)	0.7592
High	7833	1.004 (1.002, 1.007)	0.0001
AST				0.0063
Low	6783	0.998 (0.994, 1.003)	0.4820
High	8630	1.005 (1.003, 1.007)	< 0.0001
GGT				0.5222
Low	7245	1.002 (0.997, 1.007)	0.4094
High	8168	1.004 (1.001, 1.006)	0.0012

ISSN: 1472-6823