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Table 1 Patient’s demographics lab data and adenoma characteristics at the beginning of the study

From: Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a randomized controlled trial

 

PEA (n = 68)

PTx (n = 68)†

Overall (n = 68)

Complete response (n = 62)

Partial response (n = 4)

Disease persistence (n = 2)

Demographic

Female sex, n (%)

58 (85.2%)

53 (85.4%)

3 (75%)

2 (100%)

55 (80.8%)

Age (years)

56.2 ± 10.4

56.4 ± 10.3

49.5 ± 12.0

62.0 ± 5.6

52.7 ± 11.0

BMI

27.6 ± 5.7

27.5 ± 5.9

26.1 ± 2.7

32.5 ± 0.7

27.5 ± 5.7

Lab

Serum-adjusted Ca (mg/dL)

Reference range [8.6–10.2 mg/dL]

10.5 ± 0.8

10.5 ± 0.8

10.4 ± 0.61

10.2 ± 0.07

10.5 ± 1.1

Normocalcemic HP, n (%)

33 (48.5%)

29 (46.7%)

2 (50%)

2 (100%)

33 (48.5%)

Phosphorus

Reference range [3.0–4.5 mg/dL]

2.6 ± 0.4

2.6 ± 0.4

3.0 ± 0.5

2.4 ± 0.4

2.6 ± 0.4

PTH (pg/mL)

Reference range [10–65 pg/mL]

146.4 ± 62.9

144.4 ± 60.6

137.2 ± 88.9

225.5 ± 68.5

149.1 ± 50.1

25-hydroxy vitamin D (ng/mL)

Reference range [30–60 ng/mL]

36.2 ± 13.6

36.7 ± 13.8

24.6 ± 4.1

44.9 ± 10.0

32.8 ± 11.3

Alkaline phosphatase (IU/L)

Reference range [30–120 U/L]

221.6 ± 61.8

220.0 ± 60.0

201.2 ± 45.8

310.0 ± 113.1

219.7 ± 63.4

Adenoma characteristics

Adenoma localization by ultrasound

Upper right, n (%)

13 (19.1%)

   

10 (14.7%)

Lower right, n (%)

19 (27.9%)

   

16 (23.5%)

Upper left, n (%)

12 (17.6%)

   

11 (16.1%)

Lower left, n (%)

24 (35.2%)

   

31 (45.5%)

Maximum adenoma diameter (mm)

12.4 ± 3.8

11.9 ± 3.5

17.9 ± 4.9

15.3 ± 0.42*

13.7 ± 3.8

Volume (mm3)

398.3 ± 351.6

347.8 ± 287.4

739.5 ± 556.3

1282.8 ± 360.2**

502.5 ± 285.8

  1. * and ** ANOVA between alcohol ablation subgroups with p-values of 0.004 and < 0.001, respectively
  2. † Independent t-test or Chi-square between Surgery and Alcohol ablation (overall) was used for comparison and none of the p-values was statistically significant