Table 2 Endogenous sex hormones and the revised Framingham Stroke Risk Profile, results from linear regression model. N = 133

Model 1 Crude

0.094

-0.037

0.225

0.159

Model 2 (adjusted for BMI)

0.155

0.025

0.285

0.020

Model 3 (adjusted for BMI, CRP and cholesterol)

0.150

0.017

0.283

0.027

Model 3 + adjustment for SHBG

0.150

0.013

0.288

0.032

17-α-OH-progesterone

Model 1 Crude

0.112

-0.024

0.248

0.106

Model 2 (adjusted for BMI)

0.146

0.014

0.277

0.031

Model 3 (adjusted for BMI, CRP and cholesterol)

0.138

0.004

0.273

0.044

Model 3 + adjustment for SHBG

0.139

0.004

0.274

0.044

Estrone

Model 1 Crude

0.208

0.081

0.336

0.002

Model 2 (adjusted for BMI)

0.167

0.037

0.297

0.013

Model 3 (adjusted for BMI, CRP and cholesterol)

0.167

0.034

0.301

0.014

Model 3 + adjustment for SHBG

0.181

0.043

0.318

0.010

Estradiol

Model 1 Crude

0.170

0.034

0.305

0.015

Model 2 (adjusted for BMI)

0.088

-0.067

0.243

0.262

Model 3 (adjusted for BMI, CRP and cholesterol)

0.091

-0.069

0.252

0.263

Model 3 + adjustment for SHBG

0.098

-0.061

0.256

0.224

β

2.5%CI

97.5%CI

p

Testosterone

Model 1 Crude

0.080

-0.052

0.212

0.235

Model 2 (adjusted for WHR)

0.152

0.026

0.278

0.018

Model 3 (adjusted for WHR, CRP and cholesterol)

0.157

0.031

0.283

0.015

Model 3 + adjustment for SHBG

0.163

0.029

0.296

0.017

DHEA

Model 1 Crude

-0.102

-0.235

0.029

0.127

Model 2 (adjusted for WHR)

-0.084

-0.209

0.042

0.190

Model 3 (adjusted for WHR, CRP and cholesterol)

-0.084

-0.211

0.042

0.187

Model 3 + adjustment for SHBG

-0.071

-0.201

0.059

0.279

DHT

Model 1 Crude

-0.079

-0.212

0.053

0.238

Model 2 (adjusted for WHR)

-0.022

-0.151

0.108

0.742

Model 3 (adjusted for WHR, CRP and cholesterol)

-0.009

-0.141

0.123

0.893

Model 3 + adjustment for SHBG

-0.011

-0.147

0.126

0.878

Androstenedione

Model 1 Crude

0.024

-0.112

0.159

0.730

Model 2 (adjusted for WHR)

0.010

-0.119

0.139

0.879

Model 3 (adjusted for WHR, CRP and cholesterol)

0.010

-0.118

0.140

0.869

Model 3 + adjustment for SHBG

0.013

-0.116

0.143

0.840

Sex hormone binding globulin

Model 1 Crude

-0.064

-0.200

0.073

0.358

Model 2 (adjusted for BMI)

0.017

-0.126

0.161

0.812

Model 3 (adjusted for BMI, CRP and cholesterol)

0.024

-0.121

0.170

0.744