Correlation between circulating microRNAs and vascular biomarkers in type 2 diabetes based upon physical activity: a biochemical analytic study

Table 2 Changes in glucose control traits and vascular endothelial biomarkers in type 2 diabetic patients with different PA (M ± SD)

Parameters	Mild –PA (≤ 500 METs min/ week)	Moderate –PA (500–2500 METs-min/week)	Physically active (≥ 2500 METs-min/week)
FBS (mg/dl)	215 ± 12.1	168 ± 21.3^**	136.4 ± 16.3^**
HbA1c (%)	9.5 ± 2.1	7.9 ± 0.85^**	6.7 ± 0.58^**
FINS (mUI/ml)	18.7 ± 3.4	14.2 ± 3.1^**	12.2 ± 2.6^**
HOMA-IR	5.5 ± 1.4	4.3 ± 1.7^**	2.8 ± 1.2^**
VEGF (pg/ml)	89.7 ± 3.4	76.2 ± 1.76^**	62.7 ± 2.3^**
ApoAI (mg/dL)	1.8 ± 0.52	1.5 ± 0.38^**	1.2 ± 0.46^**
ApoB (mg/dL)	1.2 ± 0.26	0.98 ± 0.31^**	0.75 ± 0.24^**
ApoB /apoA-I ratio	0.67 ± 0.31	0.65 ± 0.33^*	0.62 ± 0.25^*

Notes: All values represent mean ± standard deviation. ^*P < 0.05; ^**P < 0.01. A Student’s t-test or the Mann-Whitney U test was used for comparing diabetic participants with different PA-scorers
Abbreviations: HOMA: homeostatic model assessment, IR: insulin resistance, VEGF: Vascular endothelial growth factor (vascular molecule), ApoA-I: apolipoprotein A-I, ApoB: apolipoprotein B, FINS: fasting serum insulin, HbA1c: Glycated hemoglobinA1c, PA: physical activity

ISSN: 1472-6823