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Table 1 Baseline characteristics of the study population according to the SUA/Cr

From: Serum uric acid to creatinine ratio as a predictor of insulin resistance, β cell function, and metabolic syndrome in normal Korean adults: a cross-sectional study

SUA/Cr

 

Total (n = 14,984)

1st tertile (< 5.87) (n = 4,942)

2nd tertile (5.87 ~ 7.11) (n = 4,941)

3rd tertile (> 7.11) (n = 5,101)

P-Value

Age(years)

51.1 ± 16.8

54.0 ± 16.7

50.7 ± 16.6

48.6 ± 16.7

< 0.001

Sex(men)

6,560(43.8%)

2,102(42.5%)

2,138(43.3%)

2,320(45.5%)

0.459

Smoking

463(3.1%)

165(3.4%)

144(2.9%)

154(3.0%)

0.603

Drinking

1,691(11.3%)

648(13.1%)

534(10.8%)

509(10.0%)

0.004

Exercising

220(1.5%)

52(1.1%)

66(1.3%)

102(2.0%)

0.011

MetS

3,181(21.2%)

788(15.9%)

978(19.8%)

1,415(27.7%)

< 0.001

SBP(mmHg)

119.1 ± 16.3

118.5 ± 16.8

118.5 ± 16.0

120.1 ± 15.9

0.623

DBP(mmHg)

75.4 ± 9.9

74.3 ± 9.7

75.1 ± 9.6

76.5 ± 10.2

< 0.001

WC(cm)

83.7 ± 10.5

81.7 ± 10.1

83.0 ± 10.0

86.2 ± 10.7

< 0.001

BMI(kg/m2)

24.0 ± 3.6

23.2 ± 3.3

23.7 ± 3.4

25.0 ± 4.0

< 0.001

FPG(mg/dl)

98.4 ± 17.0

98.3 ± 19.5

97.7 ± 15.0

99.2 ± 16.1

0.076

HbA1c(%)

5.7 ± 0.6

5.7 ± 0.7

5.6 ± 0.5

5.7 ± 0.6

0.309

Insulin(mU/L)

9.2 ± 9.1

8.1 ± 7.1

8.6 ± 7.2

10.8 ± 11.8

< 0.001

HOMA-IR

2.3 ± 3.1

2.0 ± 2.2

2.2 ± 2.3

2.8 ± 4.1

< 0.001

HOMA-β

97.4 ± 88.3

86.9 ± 82.8

92.3 ± 68.1

112.5 ± 106.8

< 0.001

TC(mg/dl)

194.1 ± 37.3

190.7 ± 36.8

194.3 ± 37.5

197.2 ± 37.3

< 0.001

HDL-C(mg/dL)

52.8 ± 12.8

54.5 ± 13.2

52.9 ± 12.6

51.0 ± 12.3

< 0.001

LDL-C(mg/dL)

115.7 ± 34.9

114.1 ± 33.2

116.8 ± 34.7

116.1 ± 36.5

< 0.001

TG(mg/dL)

128.3 ± 103.9

110.2 ± 72.0

123.2 ± 92.7

150.7 ± 132.4

< 0.001

Creatinine(mg/dL)

0.8 ± 0.2

0.9 ± 0.3

123.2 ± 92.7

0.7 ± 0.2

< 0.001

SUA(mg/dL)

5.1 ± 1.4

4.3 ± 1.1

5.2 ± 1.1

6.1 ± 1.3

< 0.001

  1. Kruskal-Wallis test and Mann-Whitney test were used to compare groups divided according to SUA/Cr values
  2. Quantitative data are presented as mean ± standard deviation, and categorical variables are expressed as absolute values (percentages)
  3. Abbreviations: BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting glucose, HDL-C high-density lipoprotein-cholesterol, HOMA-β homeostasis model assessment-beta cell secretory function, HOMA-IR homeostasis model assessment-insulin resistance, LDL-C low-density lipoprotein-cholesterol, MetS metabolic syndrome, SUA serum uric acid, SUA/Cr serum uric acid to creatinine ratio, TC total cholesterol, TG Triglyceride