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Table 3 Factors affecting insulin resistance(HOMA-IR), β cell dysfunction(HOMA-β), and incidence of MetS investigated by binary logistic regression analysis

From: Serum uric acid to creatinine ratio as a predictor of insulin resistance, β cell function, and metabolic syndrome in normal Korean adults: a cross-sectional study

 

Insulin resistance(HOMA-IR)

β cell dysfunction(HOMA-β)

Incidence of MetS

P-Value

Odds ratio

95% CI

P-Value

Odds ratio

95% CI

P-Value

Odds ratio

95% CI

Age(years)

0.026

1.002

1.000–1.005

< 0.001

0.995

0.993–0.997

< 0.001

1.014

1.009–1.019

Sex(men)

0.013

1.096

1.019–1.178

   

< 0.001

4.705

4.126–5.365

Smoking

< 0.001

1.493

0.960–2.323

   

0.023

0.378

0.163–0.876

Drinking

< 0.001

0.966

0.631–1.478

      

Exercising

< 0.001

0.785

0.591–1.043

      

SBP(mmHg)

< 0.001

1.020

1.018–1.023

   

< 0.001

1.013

1.008–1.018

DBP(mmHg)

< 0.001

1.035

1.032–1.039

   

< 0.001

1.062

1.053–1.071

WC(cm)

< 0.001

1.121

1.115–1.126

< 0.001

1.009

1.005–1.013

< 0.001

1.124

1.115–1.133

HbA1c(%)

< 0.001

3.627

3.326–3.956

< 0.001

1.359

1.260–1.466

< 0.001

2.239

1.999–2.509

HDL-C(mg/dL)

< 0.001

0.950

0.947–0.953

   

< 0.001

0.901

0.895–0.908

LDL-C(mg/dL)

< 0.001

0.998

0.997–0.999

0.001

0.998

0.997–0.999

0.005

1.002

1.001–1.004

TG(mg/dL)

< 0.001

1.007

1.007–1.008

   

< 0.001

1.012

1.011–1.013

SUA/Cr

< 0.001

1.231

1.204–1.259

0.004

1.033

1.011–1.057

0.001

1.065

1.026–1.106

  1. Multivariate logistic regression analysis was conducted to show the association between SUA/Crand HOMA-IR, HOMA-β, and MetS
  2. Only statistically significant variables were presented in the table
  3. Abbreviations: CI confidence interval, DBP diastolic blood pressure, HDL-C high-density lipoprotein-cholesterol, HOMA-β homeostasis model assessment-beta cell secretory function, HOMA-IR homeostasis model assessment-insulin resistance, LDL-C low-density lipoprotein-cholesterol, MetS metabolic syndrome, SBP systolic blood pressure, SUA/Cr serum uric acid to creatinine ratio, TG Triglyceride