Table 2 The results of the heterogeneity and pleiotropy analysis
Outcome | Exposure | Pleiotropy test | Heterogeneity test | |||
|---|---|---|---|---|---|---|
Intercept | SE | P Value | Q | P Value | ||
SIDD | Family Streptococcaceae | -0.07 | 0.08 | 0.405 | 9.76 | 0.779 |
SIDD | Genus Collinsella | -0.07 | 0.14 | 0.629 | 4.45 | 0.487 |
SIDD | Genus Subdoligranulum | 0.1 | 0.08 | 0.243 | 9.78 | 0.712 |
SIDD | Species sp_AP11 | 0.03 | 0.12 | 0.78 | 4.49 | 0.722 |
SIDD | Species ramulus | 0.01 | 0.12 | 0.967 | 2.79 | 0.903 |
SIDD | Species longicatena | -0.46 | 0.45 | 0.347 | 4.19 | 0.758 |
SIRD | Genus Subdoligranulum | -0.01 | 0.08 | 0.941 | 9.03 | 0.771 |
SIRD | Genus Holdemania | / | / | / | 0.11 | 0.737 |
SIRD | Species johnsonii | 0.04 | 0.12 | 0.741 | 6.46 | 0.596 |
SIRD | Species bacterium_8_1_57FAA | 0 | 0.08 | 0.996 | 8.66 | 0.732 |
MOD | Class Clostridia | -0.04 | 0.1 | 0.693 | 1.85 | 0.763 |
MOD | Genus Coprobacter | -0.18 | 0.14 | 0.244 | 5.76 | 0.451 |
MOD | Genus Subdoligranulum | 0.01 | 0.08 | 0.87 | 6.96 | 0.904 |
MOD | Order Actinomycetales | / | / | / | 2.01 | 0.157 |
MOD | Order Clostridiales | -0.04 | 0.1 | 0.694 | 1.85 | 0.763 |
MOD | Species fastidiosus | -0.17 | 0.13 | 0.251 | 5.75 | 0.452 |
MOD | Species xylanisolvens | -0.03 | 0.08 | 0.755 | 4.67 | 0.862 |
MOD | Species catus | 0.15 | 0.11 | 0.262 | 2.53 | 0.773 |
MARD | Family Lactobacillaceae | 0.06 | 0.07 | 0.442 | 3.12 | 0.959 |
MARD | Family Lachnospiraceae | -0.05 | 0.08 | 0.552 | 9.65 | 0.472 |
MARD | Genus Gordonibacter | -0.11 | 0.16 | 0.556 | 3.65 | 0.302 |
MARD | Species pamelaeae | -0.11 | 0.16 | 0.547 | 3.67 | 0.299 |
MARD | Species sp_AP11 | 0.07 | 0.09 | 0.48 | 6.29 | 0.506 |
MARD | Species bacterium_D16 | 0.16 | 0.09 | 0.13 | 5.97 | 0.426 |
MARD | Species plebeius | 0.02 | 0.08 | 0.793 | 2.61 | 0.856 |
MARD | Species stercoris | -0.11 | 0.18 | 0.585 | 2.07 | 0.723 |