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Table 3 Subgroup analysis of hypoglycemia incidence

From: Effect of liberal glucose control on critically ill patients: a systematic review and meta-analysis

Subgroup

Studies

RR (95% CI),P

I2,PHeterogeneity

Pregression

All studies

8

1.23 (1.03, 1.48),0.001

61.4%,0.008

 

The diagnostic criteria for hypoglycemia

   

0.047

< 40 mg/dL

5

0.29(0.14,0.59),0.001

82.6%,<0.001

 

< 72 mg/dL

5

0.63(0.43,0.95),0.026

25.8%,<0.001

 

Control group target blood glucose

   

0.012

80–110 mg/dl

3

0.23 (0.11,0.51),<0.001

88.0%,<0.001

 

108–180 mg/dl

5

0.65(0.46, 0.92),0.015

9.4%,0.357

 

Diabetes

   

0.012

Partial diabetic

3

0.23 (0.11,0.51),<0.001

88.0%,<0.001

 

Diabetic

5

0.65(0.46, 0.92),0.015

9.4%,0.357

 

Study type

   

0.003

RCT

4

0.25 (0.13, 0.47),<0.001

84.2%,<0.001

 

Non-RCT

4

0.77 (0.54, 1.11),0.161

0.0%,0.849

 
  1. Abbreviations: RR, relative risk; Cl, confidence interval