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Table 1 Clinical characteristics of 542 PTC patients included in the present study

From: Nomogram for predicting the risk of cervical lymph node metastases and recurrence in papillary thyroid carcinoma based on the thyroid differentiation score system and clinical characteristics

Clinical characteristics

Total No. (%)

Training No. (%)

Validation No. (%)

P

Sex

   

0.70

 Female

391 (72.14)

276 (72.63)

115 (70.99)

 

 Male

151 (27.86)

104 (27.37)

47 (29.01)

 

Age (year)

   

0.79

 < 55

379 (69.93)

267 (70.26)

112 (69.14)

 

 ≥ 55

163 (30.07)

113 (29.74)

50 (30.86)

 

Dimension (median [p25, p75])

2.50 [1.50, 3.60]

2.5 [1.50, 3.52]

2.4 [1.50, 3.70]

0.92

Multifocality

   

0.55

 No

252 (46.49)

173 (45.53)

79 (48.77)

 

 Yes

222 (40.96)

158 (41.58)

64 (39.51)

 

 NA

68 (12.55)

49 (13.09)

19 (11.72)

 

Bilaterality

   

0.92

 No

362 (66.79)

253 (66.58)

109 (67.28)

 

 Yes

111 (20.48)

77 (20.26)

34 (20.99)

 

 NA

69 (12.73)

50 (13.16)

19 (11.73)

 

Extrathyroidal invasion

   

0.40

 No

300 (55.35)

215 (56.58)

85 (52.47)

 

 Yes

162 (29.89)

110 (28.95)

52 (32.10)

 

 NA

80 (14.76)

55 (14.47)

25 (15.43)

 

Lymphocytic thyroiditis

   

0.11

 No

340 (62.73)

232 (61.05)

108 (66.67)

 

 Yes

83 (15.31)

64 (16.84)

19 (11.73)

 

 NA

119 (21.96)

84 (22.11)

35 (21.60)

 

Histological type

   

0.94

 Classic papillary

366 (67.53)

257 (67.63)

109 (67.28)

 

 Other subtypes

176 (32.47)

123 (32.37)

53 (32.72)

 

TDS (median [p25, p75])

-0.02 [-0.36, 0.31]

-0.02 [-0.35, 0.32]

-0.04 [-0.37, 0.29]

0.71

Excised cervical LN number

6 [2, 16.5]

6 [3.00, 15.75]

5 [2.00, 19.00]

0.65

(median [p25, p75])

Radioiodine Therapy

   

0.32

 No

73 (13.47)

46 (12.11)

27 (16.67)

 

 Yes

142 (26.20)

99 (26.05)

43 (26.54)

 

 NA

327 (60.33)

235 (61.84)

92 (56.79)

 

Preoperative LN scan

   

0.90

 No

114 (21.03)

79 (20.79)

35 (21.60)

 

 Yes

336 (61.99)

235 (61.84)

101 (62.35)

 

 NA

92 (16.98)

66 (17.37)

26 (16.05)

 

OS status

   

0.34

 Live

437 (80.63)

307 (80.79)

130 (80.25)

 

 Dead

13 (2.39)

7 (1.84)

6 (3.70)

 

 NA

92 (16.98)

66 (17.37)

26 (16.05)

 

Recurrence

   

0.60

 No

396 (73.06)

278 (73.16)

118 (72.84)

 

 Yes

54 (9.96)

36 (9.47)

18 (11.11)

 

 NA

92 (16.98)

66 (17.37)

26 (16.05)

 

CLNM

   

0.71

 No

281 (51.85)

199 (52.37)

82 (50.62)

 

 Yes

261 (48.15)

181 (47.63)

80 (49.38)

 

LLNM

   

0.49

 No

412 (76.01)

292 (76.84)

120 (74.07)

 

 Yes

130 (23.99)

88 (23.16)

42 (25.93)

 
  1. NA: not available, p25: 25th percentile, p75: 75th percentile, TDS: thyroid differentiation score, LN: lymph node, OS: overall survival, CLNM: central lymph node metastasis, LLNM: lateral lymph node metastasis