Table 1 Association between thyroid Nodule Presence and various demographic and clinical variables
Variable | Overall, N = 4,1211 | Thyroid nodule | p-value2 | |
|---|---|---|---|---|
No,N = 2,9921 | Yes,N = 1,1291 | |||
Demographic Variables | ||||
Gender | < 0.001 | |||
Female | 2,127 (52%) | 1,450 (48%) | 677 (60%) | |
Male | 1,994 (48%) | 1,542 (52%) | 452 (40%) | |
Age (years) | 44.7 (9.36) | 43.5 (8.84) | 47.9 (9.93) | < 0.001 |
BMI (kg/m²) | 27.0 (4.32) | 26.9 (4.43) | 27.2 (4.02) | 0.017 |
Clinical Variables | ||||
Metabolic Syndrome | 173 (4.2%) | 113 (3.8%) | 60 (5.3%) | 0.028 |
MAP (mmHg) | 94.7 (12.96) | 94.2 (12.69) | 96.1 (13.56) | < 0.001 |
Systolic blood pressure (mmHg) | 107.3 (14.79) | 106.6 (14.31) | 109.1 (15.83) | < 0.001 |
diastolic blood pressure (mmHg) | 69.3 (9.18) | 69.2 (8.97) | 69.5 (9.72) | 0.7 |
Diabetes | 246 (6.0%) | 152 (5.1%) | 94 (8.3%) | < 0.001 |
Hypertension | 452 (11%) | 273 (9.1%) | 179 (16%) | < 0.001 |
Cardiac Disease | 0 (0%) | 0 (0%) | 0 (0%) | |
Myocardial Infarction | 15 (0.4%) | 10 (0.3%) | 5 (0.4%) | 0.6 |
Thyroid Disease | 279 (6.8%) | 145 (4.8%) | 134 (12%) | < 0.001 |
Pregnancy Hypertension | 95 (2.3%) | 63 (2.1%) | 32 (2.8%) | 0.2 |
Pregnancy Diabetes | 64 (1.6%) | 43 (1.4%) | 21 (1.9%) | 0.3 |
CVD History | 26 (0.6%) | 18 (0.6%) | 8 (0.7%) | 0.7 |
WHR Category | < 0.001 | |||
High Risk | 3,357 (81%) | 2,398 (80%) | 959 (85%) | |
Moderate Risk | 757 (18%) | 587 (20%) | 170 (15%) | |
Low Risk | 7 (0.2%) | 7 (0.2%) | 0 (0%) | |
Laboratory Measurements | ||||
FBG (mg/dL) | 99.9 (25.97) | 99.1 (24.98) | 102.2 (28.30) | < 0.001 |
TG (mg/dL) | 126.7 (78.11) | 127.2 (79.02) | 125.4 (75.69) | 0.7 |
CHOL (mg/dL) | 178.9 (35.67) | 178.3 (35.47) | 180.3 (36.17) | 0.10 |
HDLC (mg/dL) | 55.5 (12.10) | 55.3 (11.99) | 56.0 (12.38) | 0.11 |
Thyroid Stimulating Hormone | 1.9 (1.86) | 1.8 (1.90) | 2.0 (1.74) | < 0.001 |
Thyroid-Related Variables | ||||
Thyroid Family History | 1,073 (26%) | 754 (25%) | 319 (28%) | 0.046 |
Thyroid disease History | 274 (6.7%) | 183 (6.2%) | 91 (8.1%) | 0.039 |
Hypothyroidism | 158 (3.9%) | 119 (4.1%) | 39 (3.5%) | 0.4 |
Hyperthyroidism | 64 (1.6%) | 37 (1.3%) | 27 (2.4%) | 0.010 |
Goiter | 27 (0.7%) | 7 (0.2%) | 20 (1.8%) | < 0.001 |
Hashimoto | 10 (0.2%) | 6 (0.2%) | 4 (0.4%) | 0.5 |
Behavioral Variables | ||||
Current Smoking | 217 (65%) | 157 (67%) | 60 (62%) | 0.4 |
Alcohol consumption | 64 (1.6%) | 44 (1.5%) | 20 (1.8%) | 0.5 |