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Table 2 Comparison of liver enzymes among study groups

From: The relationship between hepatic enzymes, prediabetes, and diabetes in the Azar cohort population

 

Non diabetes

Pre-diabetes

Diabetes

*P

Mean ± SD

Mean ± SD

Mean ± SD

AST(IU/l)

a22.17 ± 9.87

a22.59 ± 8.70

b22.86 ± 11.37

0.001

 Median (interquartile range)

20(8)

21(8)

20(10)

 

ALT(IU/l)

c23.75 ± 13.79

c25.76 ± 13.12

c26.82 ± 14.56

< 0.001

 Median (interquartile range)

21(12)

23(14)

23(14)

 

GGT(IU/l)

c22.99 ± 17.80

c26.31 ± 19.22

c31.36 ± 30.37

< 0.001

 Median (interquartile range)

18(13)

21(15)

25(14)

 

ALP(IU/l)

c184±54.99

c197.23 ± 56.56

c205.23 ± 61.52

< 0.001

 Median (interquartile range)

177(68)

189(73)

201(77)

 
 

N(%)

N(%)

N(%)

 

AST(IU/L)

   

< 0.001

 Q1(≤ 17)

3138(30.2)

634(26.6)

702(33.6)

 

 Q2(18–20)

2318(22.3)

527(22.1)

399(19.1)

 

 Q3(21–25)

2666(25.7)

636(26.7)

452(21.6)

 

 Q4(≥ 26)

2269(21.8)

585(24.6)

539(25.8)

 

ALT (IU/L)

   

< 0.001

 Q1 (≤ 16)

2826(27.2)

502(21.1)

366(17.5)

 

 Q2(17–21)

2810(27)

585(24.6)

528(25.2)

 

 Q3(22–29)

2516(24.2)

639(26.7)

567(27.1)

 

 Q4(≥ 30)

2239(21.5)

659(27.7)

631(30.2)

 

GGT(IU/L)

   

< 0.001

 Q1(≤ 14)

3079(29.6)

488(20.5)

289(13.8)

 

 Q2(15–20)

3001(28.9)

614(25.8)

445(21.3)

 

 Q3(21–29)

2197(21.1)

625(26.2)

599(28.6)

 

 Q4(≥ 30)

2114(20.3)

655(27.5)

759(36.3)

 

ALP(IU/L)

   

< 0.001

 Q1(≤ 149

2894(27.9)

473(19.9)

371(17.7)

 

 Q2 (150–181)

2703(26)

577(24.2)

423(20.2)

 

 Q3(182–200)

2530(24.3)

612(25.7)

555(26.5)

 

 Q4(≥ 221)

2264(21.8)

720(30.2)

743(35.5)

 
  1. *P: Kruskal−Wallis
  2. a There is a significant difference between non−diabetes and prediabetes groups (P=0.001); b There is a significant difference between pre−diabetes and diabetes groups (P=0.007). c A significant difference exists among all groups (P<0.05)