From: The relationship between hepatic enzymes, prediabetes, and diabetes in the Azar cohort population
Pre-Diabetes | |||
---|---|---|---|
 | Crude model OR (95%CI) | Adjusted model 1 OR (95%CI) | Adjusted model 2 OR (95%CI) |
AST | Â | ||
 Quartile 1 | Reference | ||
 Quartile 2 | 1.12(0.99–1.27) | 1.05 (0.93–1.22) | 1.02(0.89–1.16) |
 Quartile 3 | 1.18(1.04–1.33) | 1.10(0.97–1.25) | 1.06(0.93–1.20) |
 Quartile 4 | 1.27(1.12–1.44) | 1.26(1.11–1.43) | 1.18(1.04–1.35) |
ALT | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.17(1.02–1.33) | 1.09(0.95–1.25) | 1.05(0.91–1.20) |
 Quartile 3 | 1.42(1.25–1.61) | 1.39(1.22–1.59) | 1.29(1.13–1.47) |
 Quartile 4 | 1.65(1.45–1.88) | 1.83(1.60–2.09) | 1.61(1.40–1.85) |
GGT | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.29(1.13–1.46) | 1.27(1.11–1.45) | 1.22(1.07–1.39) |
 Quartile 3 | 1.79(1.57–2.04) | 1.82(1.59–2.09) | 1.69(1.47–1.94) |
 Quartile 4 | 1.95(1.71–2.22) | 2.01(1.76–2.31) | 1.85(1.61–2.13) |
ALP | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.30(1.14–1.49) | 1.22(1.06–1.39) | 1.20(1.05–1.38) |
 Quartile 3 | 1.48(1.29–1.68) | 1.31(1.15–1.50) | 1.28(1.12–1.46) |
 Quartile 4 | 1.94(1.71–2.21) | 1.65(1.45–1.89) | 1.60(1.40–1.83) |
Gender | Â | Â | Â |
Male | Â | Â | Â |
AST | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.03(0.83–1.27) | 1.05(0.84–1.30) | 0.96(0.77–1.20) |
 Quartile 3 | 1.09(0.90–1.33) | 1.14(0.93–1.39) | 1.01(0.82–1.24) |
 Quartile 4 | 1.18(0.97–1.44) | 1.29(1.06–1.57) | 1.12(0.91–1.37) |
ALT | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 0.92(0.72–1.18 ) | 0.94(0.73–1.19) | 0.88(0.68–1.12) |
 Quartile 3 | 1.29(1.03–1.61) | 1.40(1.11–1.76) | 1.19(0.94–1.51) |
 Quartile 4 | 1.53(1.23–1.89) | 1.86(1.49–2.32) | 1.49(1.18–1.88) |
GGT | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.34(1.04–1.73) | 1.35(1.05–1.74) | 1.28(0.99–1.66) |
 Quartile 3 | 1.84(1.44–2.34) | 1.88(1.48–2.40) | 1.72(1.34–2.21) |
 Quartile 4 | 2.0(1.58–2.53) | 2.09(1.64–2.65) | 1.84(1.43–2.36) |
ALP | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.14(0.94–1.39) | 1.13(0.93–1.38) | 1.15(0.94–1.41) |
 Quartile 3 | 1.23(1.01–1.49) | 1.22(1.00-1.49) | 1.24(1.02–1.51) |
 Quartile 4 | 1.43(1.17–1.74) | 1.41(1.16–1.73) | 1.44(1.17–1.76) |
Female | Â | Â | Â |
AST | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.18(1.01–1.39) | 1.05(0.89–1.23) | 1.03(0.88–1.22) |
 Quartile 3 | 1.25(1.06–1.47) | 1.05(0.89–1.24) | 1.05(0.89–1.24) |
 Quartile 4 | 1.39(1.16–1.66) | 1.17(0.98–1.41) | 1.17(0.97–1.41) |
ALT | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.33(1.13–1.55) | 1.17(1.0-1.37) | 1.14(0.97–1.34) |
 Quartile 3 | 1.54(1.31–1.82) | 1.35(1.14–1.59) | 1.30(1.09–1.54) |
 Quartile 4 | 1.86(1.54–2.24) | 1.65(1.37-2.00) | 1.54(1.27–1.87) |
GGT | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.32(1.13–1.54) | 1.22(1.04–1.43) | 1.18(1.01–1.39) |
 Quartile 3 | 1.98(1.66–2.34) | 1.79(1.51–2.13) | 1.66(1.39–1.98) |
 Quartile 4 | 2.27(1.90–2.71) | 1.95(1.62–2.34) | 1.84(1.53–2.21) |
ALP | Â | Â | Â |
 Quartile 1 | Reference |  |  |
 Quartile 2 | 1.42(1.19–1.70) | 1.26(1.05–1.51) | 1.23(1.02–1.48) |
 Quartile 3 | 1.69(1.42–2.03) | 1.35(1.12–1.62) | 1.28(1.07–1.55) |
 Quartile 4 | 2.43(2.05–2.89) | 1.80(1.50–2.15) | 1.70(1.42–2.04) |