From: The relationship between hepatic enzymes, prediabetes, and diabetes in the Azar cohort population
 | Diabetes | ||
---|---|---|---|
 | Crude model OR (95%CI) | Adjusted model 1 OR (95%CI) | Adjusted model 2 OR (95%CI) |
AST | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 0.76(0.67–0.88) | 0.70(0.61–0.81) | 0.70(0.61–0.81) |
 Quartile 3 | 0.75(0.66–0.86) | 0.69(0.60–0.79) | 0.69(0.60–0.79) |
 Quartile 4 | 1.06(0.93–1.20) | 1.09(0.95–1.24) | 1.04(0.91–1.19) |
ALT | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.45(1.25–1.67) | 1.32)1.13–1.53) | 1.25(1.08–1.46) |
 Quartile 3 | 1.74(1.51-2.0) | 1.75 (1.51–2.03) | 1.56(1.34–1.82) |
 Quartile 4 | 2.17(1.89–2.50) | 2.80(2.40–3.25) | 2.29(1.97–2.66) |
GGT | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.58(1.35–1.84) | 1.54)1.31–1.81( | 1.40(1.19–1.65) |
 Quartile 3 | 2.90(2.49–3.37) | 3.08)2.62–3.61( | 2.57(2.19–3.02) |
 Quartile 4 | 3.82(3.30–4.42) | 4.36)3.72–5.10( | 3.40(2.91–3.97) |
ALP | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.22(1.05–1.41( | 1.10)0.94–1.28) | 1.09 (0.93–1.28) |
 Quartile 3 | 1.71(1.48–1.97) | 1.39(1.20–1.61) | 1.34(1.15–1.56) |
 Quartile 4 | 2.56(2.23–2.93) | 1.92(1.66–2.21) | 1.85(1.60–2.13) |
Gender | Â | Â | Â |
Male | Â | ||
AST | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 0.77(0.62–0.96) | 0.81(0.64–1.01) | 0.74(0.58–0.94) |
 Quartile 3 | 0.62(0.50–0.77) | 0.69(0.55–0.85) | 0.61(0.48–0.76) |
 Quartile 4 | 0.77(0.63–0.94) | 0.96(0.78–1.18) | 0.78(0.63–0.97) |
ALT | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.20(0.91–1.57) | 1.26(0.95–1.66) | 1.18(0.89–1.58) |
 Quartile 3 | 1.41(1.09–1.82) | 1.69(1.30–2.21) | 1.36(1.03–1.79) |
 Quartile 4 | 1.72(1.34–2.20) | 2.71(2.09–3.52) | 1.91(1.45–2.52) |
GGT | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.23(0.90–1.68) | 1.26(0.92–1.74) | 1.09(0.79–1.50) |
 Quartile 3 | 2.18(1.63–2.92) | 2.34(1.73–3.15) | 1.79(1.32–2.43) |
 Quartile 4 | 3.19(2.41–4.23) | 3.71(2.78–4.96) | 2.52(1.86–3.40) |
ALP | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.06(0.84–1.33) | 1.07(0.84–1.35) | 1.10(0.86–1.40) |
 Quartile 3 | 1.29(1.04–1.61) | 1.32(1.05–1.65) | 1.36(1.08–1.72) |
 Quartile 4 | 1.81(1.46–2.25) | 1.79(1.44–2.24) | 1.87(1.48–2.35) |
Female | Â | Â | Â |
AST | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 0.75(0.63–0.90) | 0.61(0.51–0.74) | 0.63(0.52–0.76) |
 Quartile 3 | 0.89(0.75–1.05) | 0.68(0.57–0.81) | 0.70(0.58–0.83) |
 Quartile 4 | 1.54(1.30–1.82) | 1.19(1.00-1.43) | 1.20(1.00-1.44) |
ALT | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.61(1.36–1.91) | 1.34(1.12–1.60) | 1.28(1.07–1.54) |
 Quartile 3 | 2.13(1.78–2.54) | 1.76(1.46–2.12) | 1.68(1.39–2.03) |
 Quartile 4 | 3.24(2.69–3.90) | 2.79(2.30–3.40) | 2.59(2.12–3.16) |
GGT | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.86(1.55–2.24) | 1.63(1.35–1.97) | 1.55(1.28–1.88) |
 Quartile 3 | 4.09(3.40–4.92) | 3.48(2.87–4.22) | 3.17(2.613.86) |
 Quartile 4 | 5.43(4.50–6.54) | 4.38(3.60–5.31) | 3.98(3.27–4.85) |
ALP | Â | Â | Â |
 Quartile 1 | Reference | ||
 Quartile 2 | 1.35(1.11–1.64) | 1.11(0.91–1.36) | 1.09(0.88–1.34) |
 Quartile 3 | 2.13(1.76–2.56) | 1.41(1.15–1.71) | 1.33(1.09–1.62) |
 Quartile 4 | 3.27(2.74–3.90) | 1.96(1.62–2.36) | 1.83(1.51–2.21) |