Skip to main content

Table 4 Association between liver enzymes and diabetes stratified by gender

From: The relationship between hepatic enzymes, prediabetes, and diabetes in the Azar cohort population

 

Diabetes

 

Crude model

OR (95%CI)

Adjusted model 1

OR (95%CI)

Adjusted model 2

OR (95%CI)

AST

   

 Quartile 1

Reference

 Quartile 2

0.76(0.67–0.88)

0.70(0.61–0.81)

0.70(0.61–0.81)

 Quartile 3

0.75(0.66–0.86)

0.69(0.60–0.79)

0.69(0.60–0.79)

 Quartile 4

1.06(0.93–1.20)

1.09(0.95–1.24)

1.04(0.91–1.19)

ALT

   

 Quartile 1

Reference

 Quartile 2

1.45(1.25–1.67)

1.32)1.13–1.53)

1.25(1.08–1.46)

 Quartile 3

1.74(1.51-2.0)

1.75 (1.51–2.03)

1.56(1.34–1.82)

 Quartile 4

2.17(1.89–2.50)

2.80(2.40–3.25)

2.29(1.97–2.66)

GGT

   

 Quartile 1

Reference

 Quartile 2

1.58(1.35–1.84)

1.54)1.31–1.81(

1.40(1.19–1.65)

 Quartile 3

2.90(2.49–3.37)

3.08)2.62–3.61(

2.57(2.19–3.02)

 Quartile 4

3.82(3.30–4.42)

4.36)3.72–5.10(

3.40(2.91–3.97)

ALP

   

 Quartile 1

Reference

 Quartile 2

1.22(1.05–1.41(

1.10)0.94–1.28)

1.09 (0.93–1.28)

 Quartile 3

1.71(1.48–1.97)

1.39(1.20–1.61)

1.34(1.15–1.56)

 Quartile 4

2.56(2.23–2.93)

1.92(1.66–2.21)

1.85(1.60–2.13)

Gender

   

Male

 

AST

   

 Quartile 1

Reference

 Quartile 2

0.77(0.62–0.96)

0.81(0.64–1.01)

0.74(0.58–0.94)

 Quartile 3

0.62(0.50–0.77)

0.69(0.55–0.85)

0.61(0.48–0.76)

 Quartile 4

0.77(0.63–0.94)

0.96(0.78–1.18)

0.78(0.63–0.97)

ALT

   

 Quartile 1

Reference

 Quartile 2

1.20(0.91–1.57)

1.26(0.95–1.66)

1.18(0.89–1.58)

 Quartile 3

1.41(1.09–1.82)

1.69(1.30–2.21)

1.36(1.03–1.79)

 Quartile 4

1.72(1.34–2.20)

2.71(2.09–3.52)

1.91(1.45–2.52)

GGT

   

 Quartile 1

Reference

 Quartile 2

1.23(0.90–1.68)

1.26(0.92–1.74)

1.09(0.79–1.50)

 Quartile 3

2.18(1.63–2.92)

2.34(1.73–3.15)

1.79(1.32–2.43)

 Quartile 4

3.19(2.41–4.23)

3.71(2.78–4.96)

2.52(1.86–3.40)

ALP

   

 Quartile 1

Reference

 Quartile 2

1.06(0.84–1.33)

1.07(0.84–1.35)

1.10(0.86–1.40)

 Quartile 3

1.29(1.04–1.61)

1.32(1.05–1.65)

1.36(1.08–1.72)

 Quartile 4

1.81(1.46–2.25)

1.79(1.44–2.24)

1.87(1.48–2.35)

Female

   

AST

   

 Quartile 1

Reference

 Quartile 2

0.75(0.63–0.90)

0.61(0.51–0.74)

0.63(0.52–0.76)

 Quartile 3

0.89(0.75–1.05)

0.68(0.57–0.81)

0.70(0.58–0.83)

 Quartile 4

1.54(1.30–1.82)

1.19(1.00-1.43)

1.20(1.00-1.44)

ALT

   

 Quartile 1

Reference

 Quartile 2

1.61(1.36–1.91)

1.34(1.12–1.60)

1.28(1.07–1.54)

 Quartile 3

2.13(1.78–2.54)

1.76(1.46–2.12)

1.68(1.39–2.03)

 Quartile 4

3.24(2.69–3.90)

2.79(2.30–3.40)

2.59(2.12–3.16)

GGT

   

 Quartile 1

Reference

 Quartile 2

1.86(1.55–2.24)

1.63(1.35–1.97)

1.55(1.28–1.88)

 Quartile 3

4.09(3.40–4.92)

3.48(2.87–4.22)

3.17(2.613.86)

 Quartile 4

5.43(4.50–6.54)

4.38(3.60–5.31)

3.98(3.27–4.85)

ALP

   

 Quartile 1

Reference

 Quartile 2

1.35(1.11–1.64)

1.11(0.91–1.36)

1.09(0.88–1.34)

 Quartile 3

2.13(1.76–2.56)

1.41(1.15–1.71)

1.33(1.09–1.62)

 Quartile 4

3.27(2.74–3.90)

1.96(1.62–2.36)

1.83(1.51–2.21)

  1. Model1: adjusted for age and gender (if applicable); Model2: adjusted for age, gender (if applicable), BMI, WSI, physical activity level, smoking status